Roll Call

“Acetyl L-Carnitine?”Here!ALCAR

Synthetic

Appears in 1 scanned product.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

An acetylated form of carnitine, a compound the body makes from two amino acids and uses to help move fatty acids into cells for energy production; also sold as a standalone oral supplement.

Why it’s used

Taken to support cognitive function, nerve-related comfort, and general energy metabolism, particularly in older adults.

What the evidence is for

cognitive and nerve-related outcomes in older adults or those with nerve-related conditions.

What the evidence says

The NIH ODS carnitine fact sheet notes that clinical evidence is mixed: some trials suggest benefit for peripheral nerve discomfort and mild age-related cognitive decline, but study quality and size vary and results are not consistent across the literature.

Dose studied

1.5–3 g — doses used in trials examining neuropathy and age-related cognitive decline.

Context

Trials examining nerve-related and cognitive outcomes have generally used doses of about 1.5 to 3 grams per day over periods of weeks to months; benefit in people without a documented carnitine-related condition has not been clearly established.

Rumors

  1. Cognitive and nerve-related outcomes in older adults or those with nerve-related conditions.

    Unresolvedhealth and safety evidence

    Studied in: adults with mild cognitive impairment or mild to moderate dementia.

    Measured as an outcome.