Roll Call

“Adrenals?”Here!desiccated adrenal gland, adrenal glandular

Animal-derived

Hasn’t appeared in a scanned product yet.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

Dried, powdered adrenal gland tissue, typically from cattle or pigs, sold as a "glandular" supplement.

Why it’s used

Taken by some in the belief that it supports the body's own adrenal function, often marketed around the concept of low energy or stress-related fatigue.

What the evidence says

There is no established clinical evidence that oral desiccated adrenal supplements affect adrenal hormone levels or function in humans. The broader concept of "adrenal fatigue" that this product is often marketed around is not a diagnosis recognized by mainstream endocrinology bodies, and glandular extracts have not been shown in controlled trials to produce a measurable physiological effect when taken orally.

Where we looked

There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.

  • PubMed: 1037 records · searched September 2026"Adrenals"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract])
  • PubMed: 3 records · searched September 2026"Adrenals"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH]
  • PubMed: 9632 records · searched September 2026"Adrenals"[Title/Abstract]

This says what this database holds under these terms. It is not a finding that no research exists.

Context

No standardized dose has been studied in controlled human trials.

Insufficient dataToo little has been studied to say either way.

Rumors

  1. Bovine adrenal supplements contain undisclosed thyroid and steroid hormones.

    Supports — suggestivehealth and safety evidence

    Measured as a biomarker.

    Who’s saying this

    • ConsumerLab.com, LLC — a publisher: sells memberships to supplement test results; also earns certification and seal-licensing fees
      How we know who this is
      • “ConsumerLab.com, LLC is a privately held company based in New York.” (their page)
      • “Revenues are also derived from Quality Certification Program fees, authorized use of the CL Seal of Approval, and sales of survey reports.” (their page)
  2. Adrenal glandular supports energy, stress adaptation, immune regulation and HPA-axis recovery.

    Does not support — establishedhealth and safety evidence

    Measured as an outcome.

    Who’s saying this

    • Allergy Research Group — a brand: sells hypoallergenic, practitioner-trusted supplements
      How we know who this is
      • “Allergy Research Group delivers hypoallergenic, practitioner-trusted solutions backed by 45+ years of research.” (their page)
  3. Adrenal glandulars are stimulating and addictive, causing withdrawal effects when taken long-term.

    Does not supporthealth and safety evidence

    Measured as an outcome.

    Who’s saying this

    • Lam Clinic — a professional body or practice: integrative functional medicine clinic; also sells Dr. Lam supplements
      How we know who this is
      • “Lam Clinic is an integrative functional medicine clinic.” (their page)
      • “Dr. Lam supplements are formulated to provide targeted nutritional support based on individual needs and health goals.” (their page)
  4. Adrenal glandulars treat adrenal fatigue.

    Does not support — establishedhealth and safety evidence

    Measured as an outcome.

    Who’s saying this

    • RestartMed — a brand: sells thyroid supplements formulated by Dr. Westin Childs
      How we know who this is
      • “Dr. Westin Childs is a thyroid health educator, former Doctor of Osteopathic Medicine (D.O.), and the founder of RestartMed (Dr. Westin Childs).” (their page)
      • “These supplements are formulated by thyroid expert Dr. Westin Childs for your condition: hypothyroidism, Hashimoto’s, or life after RAI & thyroidectomy.” (their page)