Apigenin
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A flavone, a type of plant pigment compound, found in chamomile flowers, parsley, celery, and other produce. Supplement versions are usually made from purified plant extract or synthesized to match the natural molecule.
Why it’s used
Taken by people hoping to support relaxation or sleep, an idea borrowed largely from chamomile's traditional use.
What the evidence says
Isolated apigenin, as a standalone supplement ingredient, has not been well studied in human trials. Most of what informs its reputation comes from chamomile tea or extract research, which is itself limited and mixed, and does not establish that concentrated apigenin alone produces the same effects.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 2 records · searched August 2026
"Apigenin"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 7165 records · searched August 2026
"Apigenin"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Human trials on chamomile (which contains apigenin among other compounds) have used varying extract doses and mostly measured mild anxiety or sleep-quality scores over a few weeks; findings are inconsistent and do not isolate apigenin's individual contribution.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.