“Beta-Glucanase?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
An enzyme that breaks down beta-glucans, a type of fiber found in grains such as oats and barley, into smaller sugar units. It is included in some digestive enzyme blends.
Why it’s used
Included in supplements to support digestion of beta-glucan-containing foods, often as part of a broader digestive enzyme complex.
What the evidence says
There is little independent clinical research on oral beta-glucanase supplementation in humans specifically for digestive symptoms. Most available evidence relates to its industrial use in food and brewing processing rather than to health outcomes from ingestion as a supplement.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 265 records · searched September 2026
"Beta-Glucanase"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 1 record · searched September 2026
"Beta-Glucanase"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 1542 records · searched September 2026
"Beta-Glucanase"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Digestive enzyme blends containing beta-glucanase have not been well studied in controlled human trials isolating this enzyme's specific contribution.
Rumors
Beta-glucanase in digestive enzyme blends improves digestion of oats, barley and wheat and enhances nutrient absorption.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Creative Enzymes — a brand: manufactures and supplies enzymes for research and industry
How we know who this is
- “Creative Enzymes uses its expertise in enzyme manufacturing to supply customers enzymes using for life science research and production of medicines, food, alcohol, beer, fruit juice, fabric, paper, leather goods, etc.” (their page)
- Creative Enzymes — a brand: manufactures and supplies enzymes for research and industry
Beta-glucanase helps break down gastrointestinal biofilms made by bacteria and yeast.
Supports — suggestivehealth and safety evidence
Studied in: rat intestinal biofilm model and in vitro Candida biofilm (non-human).
Measured as a biomarker.
- An intestinal Candida albicans model for monomicrobial and polymicrobial biofilms and effects of hydrolases and the Bgl2 ligand (Peer-reviewed) · Funded by Directorate of Research and Community Service, Ministry of Research, Technology and Higher Education of the Republic of Indonesia (government) · No conflicts declared
- Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth (Peer-reviewed) · Funding not clearly stated · Authors declare a conflict of interest
- Dispersal of single and mixed non-albicans Candida species biofilms by β-1,3-glucanase in vitro (Peer-reviewed) · Funding not checked
Who’s saying this
- SFI Health — a brand: sells nutraceuticals and supplements (Klaire Labs brand)
How we know who this is
- “Guided by a dedicated team of highly skilled professionals, SFI Health represents decades of scientific, manufacturing, sales, and marketing excellence.” (their page)
- “Through well-respected legacy brands and continuous new product innovation, SFI offers a robust, multi-category portfolio of nutraceuticals.” (their page)
Taking beta-glucanase helps people with Candida overgrowth (candidiasis).
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- An intestinal Candida albicans model for monomicrobial and polymicrobial biofilms and effects of hydrolases and the Bgl2 ligand (Peer-reviewed) · Funded by Directorate of Research and Community Service, Ministry of Research, Technology and Higher Education of the Republic of Indonesia (government) · No conflicts declared
Who’s saying this
- Creative Enzymes — a brand: manufactures and supplies enzymes for research and industry
How we know who this is
- “Creative Enzymes uses its expertise in enzyme manufacturing to supply customers enzymes using for life science research and production of medicines, food, alcohol, beer, fruit juice, fabric, paper, leather goods, etc.” (their page)
Beta-glucanase breaks down the Candida biofilm that grows in the digestive tract.
Supports — suggestivehealth and safety evidence
Studied in: rats with experimentally induced intestinal Candida albicans biofilm.
Measured as a biomarker.
- An intestinal Candida albicans model for monomicrobial and polymicrobial biofilms and effects of hydrolases and the Bgl2 ligand (Peer-reviewed) · Funded by Directorate of Research and Community Service, Ministry of Research, Technology and Higher Education of the Republic of Indonesia (government) · No conflicts declared
- Dispersal of single and mixed non-albicans Candida species biofilms by β-1,3-glucanase in vitro (Peer-reviewed) · Funding not checked
Who’s saying this
- Creative Enzymes — a brand: manufactures and supplies enzymes for research and industry
How we know who this is
- “Creative Enzymes uses its expertise in enzyme manufacturing to supply customers enzymes using for life science research and production of medicines, food, alcohol, beer, fruit juice, fabric, paper, leather goods, etc.” (their page)