Bromelain — answers to pineapple enzyme
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A mixture of protein-digesting enzymes extracted from the stem and fruit of the pineapple plant.
Why it’s used
Taken to support digestion, and sometimes marketed for reducing swelling or discomfort after minor injury or surgery.
What the evidence says
Human evidence is limited. Some small trials have examined effects on swelling and pain after dental or minor surgical procedures, but study designs and doses vary widely and results have not been consolidated into a settled conclusion by major evidence reviews.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 34 records · searched August 2026
"Bromelain"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 2113 records · searched August 2026
"Bromelain"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Studied doses and protocols vary considerably between small trials, without a consistent regimen used across the research.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.