Roll Call

“Caffeine?”Here!

AntioxidantConditioning agentPlant

Hasn’t appeared in a scanned product yet.

In personal care

The same stimulant alkaloid found in coffee, tea, and cacao, extracted or synthesized for use in topical products.

Why it’s used

It is included in skin and scalp products for its ability to tighten the appearance of skin temporarily and for its antioxidant properties; it is also marketed in hair products on the theory that it may support hair follicle activity.

What the evidence says

We haven’t found a source for this one that you can open and check, so we’re not summarizing the evidence.

Look it up yourself

We would rather point you at the shelf than summarize something you can’t check. These are the same places we search:

  • PubChem — what the substance is, chemically — names, synonyms and structure
  • PubMed — every paper indexed by the US National Library of Medicine that names it

These are starting points, not our findings — we haven’t run them for you. A substance whose name is also an ordinary word (“Heart”, “Alanine”, “Water”) will return papers that are not about the ingredient at all.

Context

Most supporting studies for hair-related effects use laboratory or ex vivo models rather than large controlled trials in people, so claims of visible hair benefits go beyond what the current evidence firmly shows.

No claims graded here yet.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

A naturally occurring stimulant found in coffee, tea, and cacao, and often added directly to supplements and energy products.

Why it’s used

Taken to increase alertness and reduce feelings of fatigue, and sometimes to support exercise performance.

What the evidence is for

improving alertness and reducing perceived fatigue at moderate doses.

What the evidence says

Evidence supports an effect on alertness and reaction time at moderate doses, and on endurance and anaerobic exercise performance in some studies of athletic populations. Effects vary by individual tolerance, habitual intake, and timing.

Dose studied

100–400 mg — doses studied for alertness and exercise performance.

Context

Studies of alertness and exercise performance have generally used doses of about 100-400 mg, often given shortly before activity; higher doses show diminishing benefit and more side effects.

Rumors

  1. Improving alertness and reducing perceived fatigue at moderate doses.

    Not gradedhealth and safety evidence

    Cited, but nothing we could open.

    What was measured is not yet noted.