“Calcium Fructoborate?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A naturally occurring form of boron bound to fructose and calcium, found in trace amounts in fruits and vegetables and produced synthetically for supplement use.
Why it’s used
Taken by some for joint comfort and to support markers of inflammation.
What the evidence says
Only a small number of small industry-associated trials have examined calcium fructoborate, generally looking at inflammatory markers or joint symptoms over short periods. This body of research is too limited in size and independence to draw firm conclusions.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 12 records · searched September 2026
"Calcium Fructoborate"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 5 records · searched September 2026
"Calcium Fructoborate"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 43 records · searched September 2026
"Calcium Fructoborate"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Available trials have used varying small daily doses and short durations, and have not been replicated at a larger scale.
Rumors
Calcium fructoborate eases joint discomfort and supports joint health.
Supports — suggestivehealth and safety evidence
Measured as an outcome.
- Short-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative, double-blind, placebo-controlled clinical study (Peer-reviewed) · Funding not checked · No conflicts declared
Who’s saying this
- Vibrant Health — a brand: sells its own dietary supplements; family-owned
How we know who this is
- “Since 1992, Vibrant Health has grown from a single science-backed formula into one of the most trusted names in wellness.” (their page)
- “Born in a barn and built on bold ideas, we’ve stayed true to a mission that puts people first: creating clean, effective supplements that help people feel their best.” (their page)
Calcium fructoborate supports cardiovascular health.
Supports — suggestivehealth and safety evidence
Studied in: healthy middle-aged adults.
Measured as a biomarker.
- Calcium Fructoborate for Bone and Cardiovascular Health (Peer-reviewed) · Funding not checked · No conflicts declared
Who’s saying this
- Inspire — a platform — posts are by its users: health community paid by clinical trial sponsors for recruitment
How we know who this is
- “Inspire is the world's largest health community.” (their page)
- “Clinical trial sponsors pay Inspire for this service.” (their page)
Calcium fructoborate supports healthy testosterone and estrogen levels.
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- The Fructoborates: Part of a Family of Naturally Occurring Sugar–Borate Complexes—Biochemistry, Physiology, and Impact on Human Health: a Review (Peer-reviewed) · Funded by Romanian National Authority for Scientific Research and Innovation, CNCS/CCCDI–UEFISCDI (government) · No conflicts declared
Who’s saying this
- Vibrant Health — a brand: sells its own dietary supplements; family-owned
How we know who this is
- “Since 1992, Vibrant Health has grown from a single science-backed formula into one of the most trusted names in wellness.” (their page)
- “Born in a barn and built on bold ideas, we’ve stayed true to a mission that puts people first: creating clean, effective supplements that help people feel their best.” (their page)
Calcium fructoborate strengthens bones and helps prevent bone loss and osteoporosis.
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- Calcium fructoborate helps control inflammation associated with diminished bone health (Peer-reviewed) · Funding not checked
- Calcium Fructoborate for Bone and Cardiovascular Health (Peer-reviewed) · Funding not checked · No conflicts declared
Who’s saying this
- Vibrant Health — a brand: sells its own dietary supplements; family-owned
How we know who this is
- “Since 1992, Vibrant Health has grown from a single science-backed formula into one of the most trusted names in wellness.” (their page)
- “Born in a barn and built on bold ideas, we’ve stayed true to a mission that puts people first: creating clean, effective supplements that help people feel their best.” (their page)
Calcium fructoborate reduces inflammation and lowers C-reactive protein (CRP).
Supports — suggestivehealth and safety evidence
Studied in: middle-aged adults (healthy or with primary osteoarthritis/stable angina) in small short-term clinical trials.
Measured as a biomarker.
- Calcium Fructoborate for Bone and Cardiovascular Health (Peer-reviewed) · Funding not checked · No conflicts declared
- Nothing Boring About Boron (Peer-reviewed) · Funding not checked
Who’s saying this
- Inspire — a platform — posts are by its users: health community paid by clinical trial sponsors for recruitment
How we know who this is
- “Inspire is the world's largest health community.” (their page)
- “Clinical trial sponsors pay Inspire for this service.” (their page)