“Campesterol?”Here!
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As a supplement
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Campesterol is a plant sterol, a naturally occurring compound structurally similar to cholesterol, found in vegetable oils, nuts, and seeds. It is usually present alongside other plant sterols like beta-sitosterol rather than isolated alone.
Why it’s used
Taken, typically as part of a mixed plant sterol blend, to support healthy LDL cholesterol levels.
What the evidence is for
supporting LDL cholesterol levels as part of mixed plant sterol intake.
What the evidence says
The cited EFSA opinion evaluated mixed plant sterols/stanols (a class that includes campesterol as a component alongside beta-sitosterol and others), not isolated campesterol, at daily intakes of 1.5-3.0 g added to approved food matrices. It concludes this mixed-sterol intake lowers blood LDL-cholesterol by around 11.3% within two to three weeks, based on a published meta-analysis and an unpublished meta-analysis of 27 randomised controlled trials, with LDL-cholesterol as a biomarker outcome rather than a clinical endpoint like heart attack or stroke. Because campesterol is not isolated or dosed separately in this evidence, the finding applies to mixed plant sterol/stanol intake as a category, not to campesterol specifically.
Dose studied
1500–2400 mg — total mixed plant sterol/stanol intake associated with LDL-lowering, per EFSA opinion.
Context
Cholesterol-lowering studies underlying regulatory claims used blends of plant sterols totaling around 1.5 to 2.4 grams per day, not campesterol as a standalone ingredient.
Rumors
Supporting LDL cholesterol levels as part of mixed plant sterol intake.
Not gradedhealth and safety evidence
Cited, but nothing we could open.
What was measured is not yet noted.