Choline
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Choline is a nutrient the body uses to build cell membranes and the neurotransmitter acetylcholine, and to support liver function. It can be synthesized in small amounts by the body but is mainly obtained through diet.
Why it’s used
Taken to meet daily choline requirements, with particular attention during pregnancy given its role in fetal development.
What the evidence is for
supporting fetal brain and liver development during pregnancy.
What the evidence says
NIH ODS describes choline as essential, noting that most people in the U.S. consume less than the adequate intake level from food alone. Evidence links adequate choline status to normal fetal brain and liver development, though direct trial evidence for supplementation benefits in already well-nourished adults is more limited.
Dose studied
425–550 mg — adult adequate intake range (women to men), per NIH ODS.
Context
Adult adequate intake is set at 425 mg per day for women and 550 mg per day for men, rising during pregnancy and lactation. A tolerable upper intake level of 3,500 mg per day has been set based on effects like low blood pressure and a fishy body odor at high doses.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.