Citrulline malate
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A compound combining the amino acid citrulline with malic acid, an organic acid involved in energy metabolism. The body converts citrulline to arginine, a precursor of nitric oxide.
Why it’s used
Taken, often before exercise, to support blood flow and exercise performance or reduce perceived fatigue during resistance training.
What the evidence is for
performance in resistance-training exercise.
What the evidence says
Some clinical trials report modest improvements in exercise performance measures, such as the number of repetitions completed or reduced muscle soreness, with citrulline malate use, though results across studies are not fully consistent and many trials are small.
Dose studied
6–8 g — pre-exercise dosing in resistance-training trials.
Context
Trials examining exercise performance have generally used single doses of around 6 to 8 grams taken before exercise.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.