Roll Call

“Cryptoxanthin?”Here!beta-cryptoxanthin

Plant

Hasn’t appeared in a scanned product yet.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

A yellow-orange carotenoid pigment found in fruits such as citrus, papaya, and persimmon. It is one of the carotenoids the body can convert into vitamin A.

Why it’s used

Taken as an antioxidant and a dietary source of provitamin A, sometimes marketed for bone or general health support.

What the evidence says

Observational studies link higher dietary beta-cryptoxanthin intake to various health markers, but these associations do not establish that a supplement form causes any benefit. Interventional trials in humans are scarce, and NIH's Office of Dietary Supplements does not maintain a dedicated fact sheet for it.

Where we looked

There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.

  • PubMed: 182 records · searched September 2026"Cryptoxanthin"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract])
  • PubMed: 46 records · searched September 2026"Cryptoxanthin"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH]
  • PubMed: 1887 records · searched September 2026"Cryptoxanthin"[Title/Abstract]

This says what this database holds under these terms. It is not a finding that no research exists.

Context

Most of the existing data come from food-frequency and blood-level studies rather than controlled supplementation trials, which limits what can be concluded about a purified supplement dose.

Insufficient dataToo little has been studied to say either way.

Rumors

  1. Beta-cryptoxanthin protects against bone loss and osteoporosis.

    Supports — suggestivehealth and safety evidence

    Measured as an outcome.

    Who’s saying this

    • Healthy Focus LLC — a publisher: natural health content on essential oils, remedies, nutrition
      How we know who this is
      • “Healthy Focus is published by Healthy Focus LLC.” (their page)
      • “We cover essential oils, natural remedies, nutrition, and everyday wellbeing, with the aim of making research easier to understand.” (their page)
  2. High doses of cryptoxanthin turn the skin orange.

    Supports — suggestivehealth and safety evidence

    Studied in: healthy women aged 21-35 years.

    Measured as an outcome.

    Who’s saying this

    • Supplements In Review — a publisher: supplement reviews; earns affiliate commissions on purchases
      How we know who this is
      • “Supplements In Review is a team of natural products industry insiders on a mission: “To help you avoid supplement scams, failures and dangers while steering you towards formulas that were made to work.”” (their page)
      • “We earn commissions from qualifying purchases made through links on this website.” (their page)
  3. Beta-cryptoxanthin helps you lose body fat and prevents abdominal obesity.

    Sources cited — check not cleared.

    Studied in: moderately obese postmenopausal Japanese women.

    Measured as an outcome.

    Who’s saying this

    • NutraIngredients — a publisher: nutrition industry trade news; part of William Reed
      How we know who this is
      • “William Reed’s NutraIngredients has been the essential online news source for the global nutrition industry for over 20 years, leveraging our digital-first position to bring powerful insights and robust information to help your business succeed.” (their page)
  4. Beta-cryptoxanthin lowers the risk of rheumatoid arthritis and fights inflammation.

    Sources cited — check not cleared.

    Measured as an outcome.

    Who’s saying this

    • Healthy Focus LLC — a publisher: natural health content on essential oils, remedies, nutrition
      How we know who this is
      • “Healthy Focus is published by Healthy Focus LLC.” (their page)
      • “We cover essential oils, natural remedies, nutrition, and everyday wellbeing, with the aim of making research easier to understand.” (their page)
  5. Beta-cryptoxanthin reduces the risk of lung cancer.

    We haven’t found evidence strong enough to support this or rule it out.

    What was measured is not yet noted.

    Who’s saying this

    • Healthy Focus LLC — a publisher: natural health content on essential oils, remedies, nutrition
      How we know who this is
      • “Healthy Focus is published by Healthy Focus LLC.” (their page)
      • “We cover essential oils, natural remedies, nutrition, and everyday wellbeing, with the aim of making research easier to understand.” (their page)