“Curcuminoids?”Here!curcumin (from turmeric)
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As a supplement
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The group of yellow-pigmented compounds found in turmeric root, of which curcumin is the main one.
Why it’s used
Taken to support joint comfort and as a general anti-inflammatory or antioxidant supplement.
What the evidence is for
joint pain and function in osteoarthritis.
What the evidence says
A 2022 systematic review and meta-analysis pooled 29 randomized controlled trials (2396 participants) covering five types of arthritis, including osteoarthritis, with curcumin or Curcuma longa extract doses of 120-1500 mg daily for 4-36 weeks. The authors report that treatment improved pain severity and markers of inflammation, but the clinical outcomes (pain, symptom severity) are not reported separately for osteoarthritis alone, and the trials span multiple arthritis diagnoses rather than isolating OA. The authors themselves caution that conclusions need to be interpreted carefully because of low study quality and small trial numbers, despite the overall positive direction of effect.
Dose studied
0.5–2 g — curcumin extract doses used in osteoarthritis trials.
Context
Trials showing benefit have generally used curcumin extract doses in the range of several hundred to about 1-2 grams per day, often paired with an absorption enhancer such as piperine or a lipid-based delivery system; trial durations are typically a few months.
Rumors
Joint pain and function in osteoarthritis.
Supports — suggestivehealth and safety evidence
Studied in: patients with arthritis (including osteoarthritis).
Measured as an outcome.
- Efficacy and Safety of Curcumin and Curcuma longa Extract in the Treatment of Arthritis: A Systematic Review and Meta-Analysis of Randomized Controlled Trial. (Peer-reviewed) · Funding not checked · No conflicts declared