“DNA?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
Deoxyribonucleic acid material, typically derived from fish, yeast, or other biological sources, included as a source of nucleic acids or nucleotides.
Why it’s used
Taken by some under the idea that dietary nucleic acids support cellular repair or genetic health, though this rationale is not grounded in established nutritional science.
What the evidence says
There is no substantial mainstream clinical evidence that ingesting DNA as a supplement has a defined physiological effect; dietary nucleic acids are broken down during digestion like other nutrients rather than being incorporated intact.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 227965 records · searched September 2026
"DNA"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 687 records · searched September 2026
"DNA"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 1324999 records · searched September 2026
"DNA"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
No standardized dosing protocols for oral DNA supplementation have been established in the research literature.
Rumors
Nucleic acid (RNA/DNA) supplements slow down the aging process.
Supports — suggestivehealth and safety evidence
A claim about nucleic acids as a group, not this substance alone.
Studied in: healthy older adults aged 60-70 years.
Measured as a biomarker.
- Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study) (Peer-reviewed) · Funded by Zhen‐ao Group Co., Ltd. (industry) · No conflicts declared
Who’s saying this
- Life Extension — a brand: sells its own vitamins and supplements
How we know who this is
- “Life Extension is a privately owned vitamin and supplement company.” (their page)
Nucleic acid supplements raise uric acid levels and can cause gout and kidney stones.
Supports — suggestivehealth and safety evidence
A claim about nucleic acids as a group, not this substance alone.
Measured as a biomarker.
- Short-Communication: Ingestion of a Nucleotide-Rich Mixed Meal Increases Serum Uric Acid Concentrations but Does Not Affect Postprandial Blood Glucose or Serum Insulin Responses in Young Adults (Peer-reviewed) · Funded by Marlow Foods Ltd. (industry) · Authors declare a conflict of interest
- Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study) (Peer-reviewed) · Funded by Zhen‐ao Group Co., Ltd. (industry) · No conflicts declared
- High dietary nucleotide consumption for one week increases circulating uric acid concentrations but does not compromise metabolic health: a randomised controlled trial (Peer-reviewed) · Funding not checked
Who’s saying this
- Life Extension — a brand: sells its own vitamins and supplements
How we know who this is
- “Life Extension is a privately owned vitamin and supplement company.” (their page)
Salmon DNA supplements support balanced mucus levels and respiratory function.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Walmart — a retailer: sells fashion, home goods and more; Walmart+ membership
How we know who this is
- “The trademarks Walmart and the Walmart Spark design are registered with the US Patent and Trademark Office.” (their page)
- “Annual members can save $380 per year!” (their page)
- Walmart — a retailer: sells fashion, home goods and more; Walmart+ membership
Taking DNA supplements during pregnancy can cause birth defects.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- RxList — a publisher: drug information resource; owned by WebMD
How we know who this is
- “RxList is an online medical resource dedicated to offering detailed and current pharmaceutical information on brand and generic drugs.” (their page)
- “RxList.com - Owned and Operated by WebMD and part of the WebMD network.” (their page)
- RxList — a publisher: drug information resource; owned by WebMD
Salmon DNA supplements stimulate collagen and elastin production, keeping skin youthful and firm.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- spafinder.com — we couldn’t open the site to see who runs it