“Flavones?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
Flavones are a broad class of plant flavonoid compounds, including apigenin and luteolin, found in foods such as parsley, celery, and citrus peel. Supplement labels sometimes list "flavones" as a general category rather than naming a specific compound.
Why it’s used
Taken as part of general antioxidant or plant-compound supplementation, though the specific reason varies depending on which flavones a product actually contains.
What the evidence says
Because "flavones" is a category rather than a single defined substance, evidence is difficult to summarize collectively. Individual flavones like apigenin and luteolin have been studied in cell and animal models with some human data, but a generic "flavones" listing does not specify which compound, amount, or evidence base applies.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 1015 records · searched September 2026
"Flavones"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 8 records · searched September 2026
"Flavones"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 5243 records · searched September 2026
"Flavones"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Research cited for individual flavones uses varying isolated compounds and doses; a blended or unspecified "flavones" ingredient cannot be matched to any single study's protocol.
Rumors
Flavone supplements slow blood clotting and can increase bleeding risk around surgery.
Unresolvedhealth and safety evidence
A claim about methoxylated flavones (a subgroup of flavones) as a group, not this substance alone.
Measured as a biomarker.
- Flavonoids (Database) · Funding not checked
Who’s saying this
- RxList — a publisher: drug information resource; owned by WebMD
How we know who this is
- “RxList is an online medical resource dedicated to offering detailed and current pharmaceutical information on brand and generic drugs.” (their page)
- “RxList.com - Owned and Operated by WebMD and part of the WebMD network.” (their page)
Eating more flavones lowers the risk of breast cancer.
Supports — suggestivehealth and safety evidence
Measured as an outcome.
- Flavonoids, Flavonoid Subclasses and Breast Cancer Risk: A Meta-Analysis of Epidemiologic Studies (Peer-reviewed) · Funded by National Natural Science Foundation of China; Youth Innovation Foundation of Third Military Medical University (government) · No conflicts declared
- Consumption of flavonoids and risk of hormone-related cancers: a systematic review and meta-analysis of observational studies (Peer-reviewed) · Funded by National Key Research and Development Program of China; National Natural Science Foundation of China; Tianjin Science and Technology Committee Foundation (government) · No conflicts declared
- Dietary flavonoid and lignan intake and breast cancer risk according to menopause and hormone receptor status in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study (Peer-reviewed) · Funding not checked
Who’s saying this
- Live Science — a publisher: science news; part of Future US Inc, a digital media group
How we know who this is
- “Live Science is part of Future US Inc, an international media group and leading digital publisher.” (their page)
Flavones have anti-inflammatory and anti-cancer effects.
Unresolvedhealth and safety evidence
Measured as an outcome.
- Flavonoids (Database) · Funding not checked
- Consumption of flavonoids and risk of hormone-related cancers: a systematic review and meta-analysis of observational studies (Peer-reviewed) · Funded by National Key Research and Development Program of China; National Natural Science Foundation of China; Tianjin Science and Technology Committee Foundation (government) · No conflicts declared
Who’s saying this
- Jinfiniti — a brand: sells biomarker testing and its own supplements
How we know who this is
- “Jinfiniti is a scientist led, data driven company that is dedicated to empowering clinicians and individuals to optimize their health, performance and longevity.” (their page)
- “Jinfiniti, a scientist-led, data-driven company, empowers clinicians and individuals to optimize health, performance, and longevity by combining advanced biomarker testing with efficacious supplements and lifestyle coaching.” (their page)
Flavones slow down how the body metabolizes drugs.
Unresolvedhealth and safety evidence
Measured as a biomarker.
- Flavonoids as CYP3A4 Inhibitors In Vitro (Peer-reviewed) · Funding not clearly stated · No conflicts declared
- Induction of cytochrome P450 2B6 activity by the herbal medicine baicalin as measured by bupropion hydroxylation (Peer-reviewed) · Funded by National Natural Science Foundation of China; China Medical Board of New York; Hunan Health Research Foundation of Traditional Chinese Medicine (government) · No conflicts declared
Who’s saying this
- Live Science — a publisher: science news; part of Future US Inc, a digital media group
How we know who this is
- “Live Science is part of Future US Inc, an international media group and leading digital publisher.” (their page)
Flavones provide antioxidant benefits.
Does not supporthealth and safety evidence
Measured as a biomarker.
- Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and biomarkers for oxidative stress in human subjects (Peer-reviewed) · Funding not checked
- Flavonoids (Database) · Funding not checked
Who’s saying this
- Live Science — a publisher: science news; part of Future US Inc, a digital media group
How we know who this is
- “Live Science is part of Future US Inc, an international media group and leading digital publisher.” (their page)