“Glycine propionyl-l-carnitine?”Here!GPLC
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A compound combining the amino acid glycine, the fatty-acid derivative carnitine, and propionate. It is a manufactured variant of carnitine designed to be more readily absorbed than plain L-carnitine.
Why it’s used
Taken by some to support exercise performance and blood flow during physical activity.
What the evidence says
A small number of published studies, largely from one or two research groups, report effects on blood flow markers and exercise performance, but the body of evidence is thin, not independently replicated at scale, and not part of a larger established literature the way plain carnitine's metabolic role is.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 3 records · searched September 2026
"Glycine propionyl-l-carnitine"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 5 records · searched September 2026
"Glycine propionyl-l-carnitine"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 13 records · searched September 2026
"Glycine propionyl-l-carnitine"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Available trials have generally used gram-level daily doses over several weeks in exercising adults, with outcomes measured around a single bout of exercise; findings have not been widely reproduced by outside laboratories.
Rumors
GPLC gives better muscle pumps, vascularity and mental focus during workouts.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- anabolicminds.com — we couldn’t open the site to see who runs it
GPLC helps you lose body fat by stopping fat being stored in fat cells.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Canadian Protein — a brand: sells whey protein and supplements made in Windsor, Ontario
How we know who this is
- “Shop Canadian Protein bulk sizes and best-selling whey proteins designed for daily use, better cost per serving, and serious value.” (their page)
- Canadian Protein — a brand: sells whey protein and supplements made in Windsor, Ontario
GPLC helps with erectile dysfunction by increasing nitric oxide and blood flow.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Allo Health — a professional body or practice: runs sexual health clinics and sells consultations, therapy and diagnostic tests
How we know who this is
- “At Allo Health, we are redefining healthcare by addressing the concerns that are often left unspoken—sexual health, mental health, and other lifestyle-driven conditions.” (their page)
- “With our growing chain of sexual health clinics, a nationwide network of sexual medicine experts, training courses, and evolving technology to provide the highest quality of care—we are defining benchmarks of success and quality in sexual health that have never existed.” (their page)
- Allo Health — a professional body or practice: runs sexual health clinics and sells consultations, therapy and diagnostic tests
GPLC improves high-intensity exercise performance and reduces lactic acid build-up.
Unresolvedhealth and safety evidence
Studied in: resistance-trained young men.
Measured as an outcome.
- Glycine propionyl-L-carnitine produces enhanced anaerobic work capacity with reduced lactate accumulation in resistance trained males (Peer-reviewed) · Funded by Sigma-tau HealthSciences, Inc. (industry) · No conflicts declared
- Long-term glycine propionyl-l-carnitine supplemention and paradoxical effects on repeated anaerobic sprint performance (Peer-reviewed) · Funded by Sigma-tau HealthSciences, Inc. (industry) · No conflicts declared
- Effect of glycine propionyl-L-carnitine on aerobic and anaerobic exercise performance (Peer-reviewed) · Funding not checked
Who’s saying this
- mensjournal.com — we couldn’t open the site to see who runs it
GPLC boosts the body's nitric oxide production, widening blood vessels and improving blood flow.
Supports — suggestivehealth and safety evidence
Measured as a biomarker.
- Glycine propionyl-L-carnitine increases plasma nitrate/nitrite in resistance trained men (Peer-reviewed) · Funded by Sigma-tau HealthSciences, Inc.; University of Memphis (industry) · No conflicts declared
- Glycine propionyl-L-carnitine modulates lipid peroxidation and nitric oxide in human subjects (Peer-reviewed) · Funding not checked
Who’s saying this
- Canadian Protein — a brand: sells whey protein and supplements made in Windsor, Ontario
How we know who this is
- “Shop Canadian Protein bulk sizes and best-selling whey proteins designed for daily use, better cost per serving, and serious value.” (their page)