“Hesperidin?”Here!a citrus flavonoid
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A flavonoid compound found naturally in citrus fruits, particularly in the peel and pith, often extracted for use in supplements.
Why it’s used
Taken by some for circulatory or antioxidant support, particularly related to vein health.
What the evidence says
Some small clinical trials, often in combination with other citrus flavonoids like diosmin, suggest possible benefit for symptoms of chronic venous insufficiency, but hesperidin alone has been studied far less, and the overall evidence base is small and not considered conclusive.
Context
Most positive findings come from flavonoid combination products rather than hesperidin used alone, which makes it difficult to attribute effects to hesperidin specifically.
Rumors
Hesperidin improves brain blood flow, cognition and memory.
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- Effects of chronic consumption of specific fruit (berries, cherries and citrus) on cognitive health: a systematic review and meta-analysis of randomised controlled trials (Peer-reviewed) · Funding not checked · No conflicts declared
Who’s saying this
- draxe.com — we couldn’t open the site to see who runs it
Hesperidin lowers high blood pressure.
Supports — suggestivehealth and safety evidence
Studied in: pre- and stage-1 hypertensive adults; adults with cardiovascular risk factors from pooled RCTs.
Measured as an outcome.
- The effects of hesperidin supplementation on cardiovascular risk factors in adults: a systematic review and dose–response meta-analysis (Peer-reviewed) · Funding not checked · No conflicts declared
- Effects of hesperidin in orange juice on blood and pulse pressures in mildly hypertensive individuals: a randomized controlled trial (Citrus study) (Peer-reviewed) · Funded by Florida Department of Citrus (government) · No conflicts declared
Who’s saying this
- draxe.com — we couldn’t open the site to see who runs it
Hesperidin supplements treat poor circulation, varicose veins and hemorrhoids.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- draxe.com — we couldn’t open the site to see who runs it
Hesperidin supplements cause stomach upset, diarrhea and headache.
Sources cited — check not cleared.
Measured as an outcome.
- The effects of hesperidin supplementation on cardiovascular risk factors in adults: a systematic review and dose–response meta-analysis (Peer-reviewed) · Funding not checked · No conflicts declared
- Effects of hesperidin in orange juice on blood and pulse pressures in mildly hypertensive individuals: a randomized controlled trial (Citrus study) (Peer-reviewed) · Funded by Florida Department of Citrus (government) · No conflicts declared
Who’s saying this
- RxList — a publisher: drug information resource; owned by WebMD
How we know who this is
- “RxList is an online medical resource dedicated to offering detailed and current pharmaceutical information on brand and generic drugs.” (their page)
- “RxList.com - Owned and Operated by WebMD and part of the WebMD network.” (their page)
Hesperidin supports the immune system, fights cancer and eases menopause symptoms.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- draxe.com — we couldn’t open the site to see who runs it