“Higenamine?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A naturally occurring plant alkaloid found in small amounts in plants such as Nandina domestica and some Aconitum species, with stimulant-like properties similar to certain beta-agonist drugs.
Why it’s used
Included in some 'fat burner' and pre-workout products with the intent of increasing energy expenditure or exercise performance.
What the evidence says
Human evidence is very sparse; most available data come from animal or in vitro studies of its beta-agonist activity rather than controlled trials in people taking it as a supplement. It is also listed as a prohibited substance in sport by anti-doping authorities.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 27 records · searched September 2026
"Higenamine"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 2 records · searched September 2026
"Higenamine"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 192 records · searched September 2026
"Higenamine"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
No consistent human dosing protocol has been established in published research.
Rumors
Higenamine is a banned beta-2 agonist that can make athletes fail doping tests.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- nsf.org — we couldn’t open the site to see who runs it
Higenamine in supplements poses cardiovascular risks.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- nsf.org — we couldn’t open the site to see who runs it