Lactoferrin
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An iron-binding protein naturally found in milk, especially colostrum, and in other body fluids like tears and saliva. Supplement forms are typically purified from cow's milk.
Why it’s used
Taken by some for immune support or to support iron status, based on its natural role in binding and helping regulate iron.
What the evidence says
Human research on lactoferrin supplementation is limited in scale, often involving small or short trials in specific groups such as infants or people with iron-deficiency anemia. There is no NIH Office of Dietary Supplements fact sheet on lactoferrin, and the overall body of evidence is not large or consistent enough to draw firm conclusions about any particular effect.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 135 records · searched August 2026
"Lactoferrin"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 10230 records · searched August 2026
"Lactoferrin"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Studies vary widely in dose, form, and population studied, which limits how well findings generalize.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.