Lithium
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A trace mineral element. In dietary supplements it usually appears as lithium orotate or lithium chloride in microgram amounts, which is a very different thing from prescription lithium carbonate, used in gram-level doses under medical supervision for certain mood disorders.
Why it’s used
Taken by some as a trace mineral thought to play a role in mood or general well-being.
What the evidence says
NIH ODS does not maintain a fact sheet on lithium as a dietary supplement. Some population-level studies have looked at lithium naturally present in drinking water and broad measures like regional suicide rates, but these are observational and say nothing about the effect of swallowing a microgram-dose supplement. There is no clinical trial evidence establishing an effect at supplement doses.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 33 records · searched August 2026
"Lithium"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 80180 records · searched August 2026
"Lithium"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Prescription lithium carbonate is dosed in grams per day and monitored with blood tests for a specific diagnosed condition. The microgram amounts sold as trace-mineral supplements are not comparable, and research on one dose level does not transfer to the other.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.