“Lithium?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A trace mineral element. In dietary supplements it usually appears as lithium orotate or lithium chloride in microgram amounts, which is a very different thing from prescription lithium carbonate, used in gram-level doses under medical supervision for certain mood disorders.
Why it’s used
Taken by some as a trace mineral thought to play a role in mood or general well-being.
What the evidence says
NIH ODS does not maintain a fact sheet on lithium as a dietary supplement. Some population-level studies have looked at lithium naturally present in drinking water and broad measures like regional suicide rates, but these are observational and say nothing about the effect of swallowing a microgram-dose supplement. There is no clinical trial evidence establishing an effect at supplement doses.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 10972 records · searched September 2026
"Lithium"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 33 records · searched September 2026
"Lithium"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 80807 records · searched September 2026
"Lithium"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Prescription lithium carbonate is dosed in grams per day and monitored with blood tests for a specific diagnosed condition. The microgram amounts sold as trace-mineral supplements are not comparable, and research on one dose level does not transfer to the other.
Rumors
Low-dose lithium orotate does not cause the side effects of prescription lithium.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Psychology Today — a publisher: psychology magazine and website with a therapist directory
How we know who this is
- “Psychology Today is the world’s largest mental health and behavioral science destination online.” (their page)
- “PsychologyToday.com is the world’s largest portal to psychotherapy; it includes free access to hundreds of thousands of professionals.” (their page)
- Psychology Today — a publisher: psychology magazine and website with a therapist directory
Low-dose lithium supplements promote healthy aging and longevity.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Life Extension — a brand: sells its own vitamins and supplements
How we know who this is
- “Life Extension is a privately owned vitamin and supplement company.” (their page)
- Life Extension — a brand: sells its own vitamins and supplements
Low-dose lithium orotate supplements help prevent cognitive decline and Alzheimer's disease.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Psychology Today — a publisher: psychology magazine and website with a therapist directory
How we know who this is
- “Psychology Today is the world’s largest mental health and behavioral science destination online.” (their page)
- “PsychologyToday.com is the world’s largest portal to psychotherapy; it includes free access to hundreds of thousands of professionals.” (their page)
- Psychology Today — a publisher: psychology magazine and website with a therapist directory
Lithium orotate supplements help regulate mood and relieve anxiety and depression.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- ageimmune.com — we couldn’t open the site to see who runs it
Low-dose lithium supplements boost brain function and cognition, especially with age.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Life Extension — a brand: sells its own vitamins and supplements
How we know who this is
- “Life Extension is a privately owned vitamin and supplement company.” (their page)
- Life Extension — a brand: sells its own vitamins and supplements