Roll Call

“Luteolin?”Here!

Plant

Hasn’t appeared in a scanned product yet.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

A flavonoid found in many plants, including celery, peppers, and chamomile, sold as an isolated supplement ingredient.

Why it’s used

Taken by some for its antioxidant properties and in the belief it may support a calm inflammatory response or seasonal allergy comfort.

What the evidence says

Laboratory and animal studies suggest luteolin has antioxidant and anti-inflammatory activity, but well-controlled human trials on oral luteolin supplementation are scarce, and there is no NIH ODS fact sheet covering it. Claims made for allergy or inflammation support in people are not well substantiated by current clinical evidence.

Where we looked

There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.

  • PubMed: 1430 records · searched September 2026"Luteolin"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract])
  • PubMed: 16 records · searched September 2026"Luteolin"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH]
  • PubMed: 8575 records · searched September 2026"Luteolin"[Title/Abstract]

This says what this database holds under these terms. It is not a finding that no research exists.

Context

Most available data come from cell-based or animal research rather than human clinical trials, limiting what can be said about effects at typical supplement doses.

Insufficient dataToo little has been studied to say either way.

Rumors

  1. Luteolin supplements improve memory and cognitive function.

    Not gradedhealth and safety evidence

    Sources cited — no verdict reached.

    What was measured is not yet noted.

    Who’s saying this

    • Neurogan Health — a brand: makes and sells longevity supplements (NMN, GHK-Cu, Fisetin, Berberine); family-owned
      How we know who this is
      • “Neurogan Health is based in San Diego, California.” (their page)
      • “Neurogan Health makes clinically-dosed longevity compounds — NMN, GHK-CU, Fisetin, Berberine — in our FDA-registered, cGMP facility in San Diego.” (their page)
  2. Luteolin stabilizes mast cells and reduces histamine release, helping histamine intolerance and MCAS.

    We haven’t found evidence strong enough to support this or rule it out.

    What was measured is not yet noted.

    Who’s saying this

    • drruscio.com — we couldn’t open the site to see who runs it
  3. Luteolin supplements can cause stomach upset and allergic reactions.

    Does not supporthealth and safety evidence

    Studied in: children with autism spectrum disorder (4-14 years old).

    Measured as an outcome.

    Who’s saying this

  4. Luteolin supplements relieve brain fog and chronic fatigue.

    Not gradedhealth and safety evidence

    Sources cited — no verdict reached.

    What was measured is not yet noted.

    Who’s saying this

    • Neurogan Health — a brand: makes and sells longevity supplements (NMN, GHK-Cu, Fisetin, Berberine); family-owned
      How we know who this is
      • “Neurogan Health is based in San Diego, California.” (their page)
      • “Neurogan Health makes clinically-dosed longevity compounds — NMN, GHK-CU, Fisetin, Berberine — in our FDA-registered, cGMP facility in San Diego.” (their page)
  5. Luteolin supplements given to children for autism disrupt the endocrine system and are dangerous.

    Not gradedhealth and safety evidence

    Sources cited — no verdict reached.

    What was measured is not yet noted.

    Who’s saying this

    • ScienceDaily — a publisher: science news site funded by advertisements and referral programs
      How we know who this is
      • “ScienceDaily features breaking news about the latest discoveries in science, health, the environment, technology, and more -- from leading universities, scientific journals, and research organizations.” (their page)
      • “Financial support for ScienceDaily comes from advertisements and referral programs.” (their page)