Roll Call

“Lycopene?”Here!

Varies by source

Hasn’t appeared in a scanned product yet.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

Lycopene is a red carotenoid pigment found naturally in tomatoes, watermelon, and other red-pink fruits. In supplements it is usually extracted from tomatoes or produced synthetically and sold as a standalone antioxidant ingredient.

Why it’s used

Taken to support general antioxidant intake and, in some formulations, marketed toward prostate health, based on observational links between tomato-rich diets and lower prostate cancer risk.

What the evidence says

Observational studies associate higher dietary lycopene or tomato intake with lower rates of some cancers, but randomized controlled trials of lycopene supplements have not consistently shown a protective effect, and no major health authority has established a specific benefit from supplemental lycopene apart from diet. The evidence for supplement form specifically is weaker than for whole-food intake.

Context

Human trials have used lycopene doses ranging widely, commonly in the 4-30 mg/day range, over periods of weeks to years, with inconsistent results across studies; differences in tomato-based versus synthetic lycopene and in absorption may explain some of the variation.

Rumors

  1. Lycopene supplements lower LDL cholesterol.

    Does not support — establishedhealth and safety evidence

    Studied in: patients with ischemic heart failure with reduced ejection fraction.

    Measured as a biomarker.

    Who’s saying this

    • Natural Health Research — an advocacy group: non-profit promoting natural health approaches; founded by NOW Foods founder Elwood Richard
      How we know who this is
      • “Building on that foundation, Elwood established Natural Health Research as an independent 501(c)(3) non-profit in 2008, dedicated to reducing major causes of death through natural, cost-effective methods.” (their page)
      • “After attending a 2002 symposium on omega-3 research by Dr. Bruce Holub, NOW Foods founder Elwood Richard launched an initiative to promote natural approaches to health.” (their page)
  2. Lycopene reduces the risk of prostate cancer.

    Unresolvedhealth and safety evidence

    Measured as an outcome.

    Who’s saying this

    • hims.com — we couldn’t open the site to see who runs it
  3. Lycopene supplements support prostate health.

    Does not support — establishedhealth and safety evidence

    Measured as a biomarker.

    Who’s saying this

    • Walmart — a retailer: sells fashion, home goods and more; Walmart+ membership
      How we know who this is
      • “The trademarks Walmart and the Walmart Spark design are registered with the US Patent and Trademark Office.” (their page)
      • “Annual members can save $380 per year!” (their page)