METHIONINE
Hasn’t appeared in a scanned product yet.
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
An essential sulfur-containing amino acid obtained from dietary protein or produced synthetically for supplement use.
Why it’s used
Taken as a building block for protein synthesis and for compounds like SAMe, sometimes marketed for liver or hair-related support.
What the evidence says
Methionine is a well-established essential nutrient obtained through normal dietary protein, but there is limited controlled human evidence for supplemental methionine taken on its own for a specific health outcome. The NIH Office of Dietary Supplements does not maintain a dedicated fact sheet on isolated methionine supplementation.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 189 records · searched August 2026
"METHIONINE"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 61364 records · searched August 2026
"METHIONINE"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Most research on methionine's physiological role comes from studies of total dietary protein and amino acid metabolism rather than trials of an isolated supplement dose.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.