“METHIONINE?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
An essential sulfur-containing amino acid obtained from dietary protein or produced synthetically for supplement use.
Why it’s used
Taken as a building block for protein synthesis and for compounds like SAMe, sometimes marketed for liver or hair-related support.
What the evidence says
Methionine is a well-established essential nutrient obtained through normal dietary protein, but there is limited controlled human evidence for supplemental methionine taken on its own for a specific health outcome. The NIH Office of Dietary Supplements does not maintain a dedicated fact sheet on isolated methionine supplementation.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 8330 records · searched September 2026
"METHIONINE"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 188 records · searched September 2026
"METHIONINE"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 61561 records · searched September 2026
"METHIONINE"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Most research on methionine's physiological role comes from studies of total dietary protein and amino acid metabolism rather than trials of an isolated supplement dose.
Rumors
Methionine makes cancer tumors grow.
Does not support — suggestivehealth and safety evidence
Measured as an outcome.
- Dietary Methionine Intake and Risk of Incident Colorectal Cancer: A Meta-Analysis of 8 Prospective Studies Involving 431,029 Participants (Peer-reviewed) · Funded by Natural Science Foundation of Hubei Province in China (government) · No conflicts declared
Who’s saying this
- NutritionFacts.org — an advocacy group: promotes whole food, plant-based diet; nonprofit
How we know who this is
- “NutritionFacts.org is a science-based nonprofit charity committed to bringing the medical literature to you, breaking down the latest in evidence-based nutrition research, and presenting the results in ways that are easy to understand.” (their page)
- “We also disseminate fact-based information through social media on the benefits of a whole food, plant-based diet for wellness, disease prevention, healthy weight management, and longevity.” (their page)
Methionine supplements promote hair growth and stronger hair.
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- Efficacy and tolerability of an oral supplement containing amino acids, iron, selenium, and marine hydrolyzed collagen in subjects with hair loss (androgenetic alopecia, AGA or FAGA or telogen effluvium). A prospective, randomized, 3‐month, controlled, assessor‐blinded study (Peer-reviewed) · Funding not checked · Authors declare a conflict of interest
- Nutraceuticals for Androgenetic Alopecia (Peer-reviewed) · Funding not clearly stated · No conflicts declared
Who’s saying this
- Darwin Nutrition — a publisher: nutrition and supplement comparison media funded by affiliation and sponsored articles
How we know who this is
- “Fondé en 2019, Darwin Nutrition est un média indépendant d’information et de comparaison sur la nutrition et les compléments alimentaires.” (their page)
- “Notre site est gratuit, financé par l’affiliation et, ponctuellement, par des articles sponsorisés clairement identifiés.” (their page)
Methionine helps prevent fatty liver.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- RTHM — a brand: sells cash-pay medication prescriptions, consultations and clinic care for chronic conditions
How we know who this is
- “RTHM is an intelligent care platform that makes it easy to gather all your health data in one place, connect the dots with AI, and affordably access the diagnostic testing, treatments, and support you need—so healing is finally within reach” (their page)
- “Pay a $49-59 consultation fee + the cost of medication at the pharmacy only if your prescription is approved.” (their page)
- RTHM — a brand: sells cash-pay medication prescriptions, consultations and clinic care for chronic conditions
Taking methionine raises homocysteine and can cause heart disease.
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- Homocysteine-lowering interventions (B-complex vitamin therapy) for preventing cardiovascular events (Peer-reviewed) · Funding not checked
Who’s saying this
- RxList — a publisher: drug information resource; owned by WebMD
How we know who this is
- “RxList is an online medical resource dedicated to offering detailed and current pharmaceutical information on brand and generic drugs.” (their page)
- “RxList.com - Owned and Operated by WebMD and part of the WebMD network.” (their page)
Methionine supplements support liver detoxification and liver fat metabolism.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Allergy Research Group — a brand: sells hypoallergenic, practitioner-trusted supplements
How we know who this is
- “Allergy Research Group delivers hypoallergenic, practitioner-trusted solutions backed by 45+ years of research.” (their page)
- Allergy Research Group — a brand: sells hypoallergenic, practitioner-trusted supplements