N-Methyltyramine
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A naturally occurring biogenic amine found in citrus peel and some plant extracts, chemically related to tyramine. It sometimes appears in supplements derived from bitter orange or citrus aurantium extracts.
Why it’s used
Included in some products marketed for energy or metabolism support, usually alongside other citrus-derived compounds like synephrine.
What the evidence says
There is very little human clinical research on N-methyltyramine specifically, whether as an isolated ingredient or at the doses found in supplements. Most available information comes from chemistry and food-science studies of citrus composition rather than trials on people.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 0 records · searched August 2026
"N-Methyltyramine"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 61 records · searched August 2026
"N-Methyltyramine"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
No standard human dosing protocol has been established in published research; it is typically present as a minor constituent of a larger citrus extract rather than dosed on its own.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.