“Naringenin?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
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A flavonoid found naturally in citrus fruits, especially grapefruit, and used in supplement form as an isolated compound.
Why it’s used
Taken to support metabolic health and as a general antioxidant, largely on the strength of laboratory and animal research.
What the evidence says
Most naringenin research to date is in cell and animal models. Human trials are few, small, and not conclusive enough to establish an effect at any particular dose.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 950 records · searched September 2026
"Naringenin"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 14 records · searched September 2026
"Naringenin"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 5449 records · searched September 2026
"Naringenin"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Where human studies exist, they use varying doses and short durations, and results have not been replicated at scale.
Rumors
Naringenin protects the liver and fights hepatitis C.
Does not supporthealth and safety evidence
Studied in: adults with NAFLD.
What was measured is not yet noted.
- Efficacy of flavonoids in non-alcoholic fatty liver disease: an updated systematic review and meta-analysis (Peer-reviewed) · Funding not clearly stated · No conflicts declared
Who’s saying this
- drweil.com — we couldn’t open the site to see who runs it
Naringenin supplements help with weight loss and metabolic syndrome.
Supports — suggestivehealth and safety evidence
Studied in: overweight/obese adults with NAFLD; single subject with untreated diabetes.
Measured as an outcome.
- Efficacy of flavonoids in non-alcoholic fatty liver disease: an updated systematic review and meta-analysis (Peer-reviewed) · Funding not clearly stated · No conflicts declared
- Naringenin Increases Insulin Sensitivity and Metabolic Rate: A Case Study (Peer-reviewed) · Funded by National Institute of General Medical Sciences of the National Institutes of Health (NIH) (grant U54 GM104940) (government) · No conflicts declared
- Safety and pharmacokinetics of naringenin: A randomized, controlled, single-ascending-dose clinical trial (Peer-reviewed) · Funding not checked
Who’s saying this
- drweil.com — we couldn’t open the site to see who runs it
Naringenin increases fat burning and regulates appetite.
Does not support — suggestivehealth and safety evidence
Studied in: single adult female with untreated type 2 diabetes.
Measured as a biomarker.
- Naringenin Increases Insulin Sensitivity and Metabolic Rate: A Case Study (Peer-reviewed) · Funded by National Institute of General Medical Sciences of the National Institutes of Health (NIH) (grant U54 GM104940) (government) · No conflicts declared
Who’s saying this
- foodstruct.com — we couldn’t open the site to see who runs it
Naringenin interacts with prescription drugs and raises their blood levels.
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- Inhibition of human CYP3A4 activity by grapefruit flavonoids, furanocoumarins and related compounds (Peer-reviewed) · Funded by Health Research Council (HRC) of New Zealand (government)
Who’s saying this
- foodstruct.com — we couldn’t open the site to see who runs it
Naringenin blocks carbohydrate absorption and lowers blood sugar and insulin spikes after meals.
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- Naringenin Increases Insulin Sensitivity and Metabolic Rate: A Case Study (Peer-reviewed) · Funded by National Institute of General Medical Sciences of the National Institutes of Health (NIH) (grant U54 GM104940) (government) · No conflicts declared
Who’s saying this
- drweil.com — we couldn’t open the site to see who runs it