Roll Call

Naringenin

Plant

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A flavonoid found naturally in citrus fruits, especially grapefruit, and used in supplement form as an isolated compound.

Why it’s used

Taken to support metabolic health and as a general antioxidant, largely on the strength of laboratory and animal research.

What the evidence says

Most naringenin research to date is in cell and animal models. Human trials are few, small, and not conclusive enough to establish an effect at any particular dose.

Where we looked

There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.

  • PubMed: 14 records · searched August 2026"Naringenin"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH]
  • PubMed: 5391 records · searched August 2026"Naringenin"[Title/Abstract]

This says what this database holds under these terms. It is not a finding that no research exists.

Context

Where human studies exist, they use varying doses and short durations, and results have not been replicated at scale.

Insufficient dataToo little has been studied to say either way.

Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.