Nickel
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A trace metallic element, naturally present in soil, water, and many foods, occasionally included in supplement formulations in trace amounts.
Why it’s used
Not commonly taken deliberately for a specific effect; its presence on a label usually reflects trace mineral content rather than an intended active ingredient.
What the evidence says
Nickel's biological role in humans, if any, is not well established, and it is not classified as an essential nutrient with a defined dietary requirement. Available research is limited and does not support a specific supplement-use claim.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 13 records · searched August 2026
"Nickel"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 59095 records · searched August 2026
"Nickel"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
No studied supplemental dosing protocol for a health benefit has been established in the literature.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.