“Palmitoleic Acid?”Here!Omega-7

Plant

Hasn’t appeared in a scanned product yet.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

A monounsaturated fatty acid naturally found in small amounts in foods like macadamia nuts and sea buckthorn, often extracted for supplements from these sources.

Why it’s used

Marketed under the name omega-7 and taken with the goal of supporting blood lipid levels and metabolic health.

What the evidence says

Human trial evidence is limited and mixed; most supportive data comes from small studies or animal research, and larger, well-controlled human trials on lipid or metabolic outcomes are lacking.

Where we looked

There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.

PubMed: 181 records · searched September 2026"Palmitoleic Acid"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract])
PubMed: 16 records · searched September 2026"Palmitoleic Acid"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH]
PubMed: 1750 records · searched September 2026"Palmitoleic Acid"[Title/Abstract]

This says what this database holds under these terms. It is not a finding that no research exists.

Context

Where human studies exist, doses and formulations vary widely between products, making it difficult to point to one 'studied' amount.

Rumors

1
Omega-7 supplements lower inflammation.
Does not support — establishedhealth and safety evidence
Measured as a biomarker.
- Effects of a palmitoleic acid concentrated oil on C-reactive protein levels in adults: A randomized, double-blind placebo-controlled clinical trial (Peer-reviewed) · Funded by Wiley Companies (industry) · No conflicts declared
- Omega-7 Mixed Fatty Acid Supplementation Fails to Reduce Serum Inflammatory Biomarkers: A Placebo-Controlled, Double-Blind Randomized Crossover Trial (Peer-reviewed) · Funded by Barlean’s Organic Oils, LLC; Bastyr University Research Institute (industry)
- Palmitoleic (16:1 n-7) acid and metabolic health: integrating observational, clinical, and mechanistic evidence (Peer-reviewed) · Funding not clearly stated · Authors declare a conflict of interest
Who’s saying this
- Goodreads — a platform — posts are by its users: book reviews and recommendations site; Goodreads LLC is a subsidiary of Amazon.com, Inc.
  How we know who this is
  “Goodreads is the world’s largest site for readers and book recommendations.” (their page)
  “Goodreads LLC is a subsidiary of Amazon.com, Inc. (“Amazon”).” (their page)
2
Omega-7 (palmitoleic acid) raises HDL and lowers LDL cholesterol, making it beneficial for heart health.
Sources cited — check not cleared.
Measured as a biomarker.
- Effects of a palmitoleic acid concentrated oil on C-reactive protein levels in adults: A randomized, double-blind placebo-controlled clinical trial (Peer-reviewed) · Funded by Wiley Companies (industry) · No conflicts declared
- Palmitoleic (16:1 n-7) acid and metabolic health: integrating observational, clinical, and mechanistic evidence (Peer-reviewed) · Funding not clearly stated · Authors declare a conflict of interest
- Palmitoleic acid paper pulled for data concerns (Journalism) · Funding not checked
Who’s saying this
- Life Extension — a brand: sells its own vitamins and supplements
  How we know who this is
  “Life Extension is a privately owned vitamin and supplement company.” (their page)
3
Omega-7 supplements relieve dry eyes.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- iherb.com — we couldn’t open the site to see who runs it
4
Omega-7 supplements help with weight loss and fight obesity-related inflammation and its consequences, such as diabetes and heart attacks.
Sources cited — check not cleared.
Measured as an outcome.
- Palmitoleic (16:1 n-7) acid and metabolic health: integrating observational, clinical, and mechanistic evidence (Peer-reviewed) · Funding not clearly stated · Authors declare a conflict of interest
- Effects of a palmitoleic acid concentrated oil on C-reactive protein levels in adults: A randomized, double-blind placebo-controlled clinical trial (Peer-reviewed) · Funded by Wiley Companies (industry) · No conflicts declared
Who’s saying this
- Life Extension — a brand: sells its own vitamins and supplements
  How we know who this is
  “Life Extension is a privately owned vitamin and supplement company.” (their page)
5
Taking omega-7 hydrates the skin and helps repair dry, cracked or inflamed skin.
Supports — suggestivehealth and safety evidence
Studied in: healthy adult women.
Measured as an outcome.
- Efficacy and safety of oral palmitoleic acid supplementation for skin barrier improvement: A 12-week, randomized, double-blinded, placebo-controlled study (Peer-reviewed) · Funding not checked
Who’s saying this
- hsnstore.eu — we couldn’t open the site to see who runs it