Roll Call

“Pantothenic Acid?”Here!Vitamin B5

Varies by source

Appears in 4 scanned products.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

An essential water-soluble B vitamin the body needs to build coenzyme A, a molecule central to metabolizing fats, carbohydrates, and proteins. It is found widely in foods including meat, vegetables, and whole grains.

Why it’s used

Taken to meet daily nutrient needs and to help ensure adequate intake, since it plays a basic role in cellular energy metabolism.

What the evidence is for

preventing dietary deficiency and supporting normal coenzyme A-dependent metabolism.

What the evidence says

According to NIH's Office of Dietary Supplements, pantothenic acid deficiency is rare because the vitamin is widespread in food, and there is an established adequate intake level for preventing deficiency. Evidence for benefits above normal dietary intake, such as for skin or athletic performance claims sometimes made for it, is limited.

Dose studied

5–5 mg — adult adequate intake level, per NIH ODS.

Context

NIH ODS lists an adequate intake of 5 mg per day for adults, with no tolerable upper intake level established due to a lack of evidence of toxicity at higher intakes.

Rumors

  1. Preventing pantothenic acid deficiency — numbness and burning in the hands and feet, headache, fatigue and disturbed sleep — which is rare outside severe malnutrition.

    Supports — establishedhealth and safety evidence

    Measured as a biomarker.

How much is a reference amount

  • 5 mg a dayfor adults 19 and over · Adequate Intake

    No upper limit has been set — the data was not sufficient to set one, which is a gap in the research rather than a finding about safety.

An AI based on usual intakes in healthy populations, not an RDA. No UL.

Every applicable line is shown because we don’t know which one is yours, and a reference intake is a target for a population, not a threshold for harm.