“Raspberry ketone?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A naturally occurring aromatic compound that gives raspberries much of their characteristic smell. The version sold in supplements is usually made synthetically, since extracting it from actual raspberries in useful quantities is impractical.
Why it’s used
Marketed and taken for weight loss, largely on the strength of its chemical similarity to synephrine and capsaicin, other compounds studied for metabolic effects.
What the evidence says
There is essentially no human clinical trial evidence for raspberry ketone taken on its own. What exists is animal and cell-based research, plus studies of combination weight-loss products that include raspberry ketone alongside several other ingredients, which cannot isolate its individual effect. The popular weight-loss claim outran the science that would support it.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 32 records · searched September 2026
"Raspberry ketone"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 1 record · searched September 2026
"Raspberry ketone"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 195 records · searched September 2026
"Raspberry ketone"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Animal studies have used doses far higher, relative to body weight, than what appears in human supplements, and no standardized human dosing protocol has been established through clinical trials.
Rumors
Raspberry ketone boosts adiponectin, a hormone that breaks down and burns body fat.
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women (Peer-reviewed) · Funded by Ultimate Wellness Systems, Inc. (industry) · Authors declare a conflict of interest
Who’s saying this
- Nature’s Craft — a brand: sells its own vitamins and supplements
How we know who this is
- “At Nature’s Craft, we pride ourselves on our wide range of supplements made with only the best ingredients to address various health concerns.” (their page)
Raspberry ketone suppresses appetite.
Does not support — suggestivehealth and safety evidence
Studied in: C57BL/6J mice (male and female) fed high-fat or low-fat diet and dosed by oral gavage with raspberry ketone.
Measured as an outcome.
- Raspberry Ketone [4-(4-Hydroxyphenyl)-2-Butanone] Differentially Effects Meal Patterns and Cardiovascular Parameters in Mice (Peer-reviewed) · Funded by NCCIH of the NIH (R01AT008933); USDA (NIFA) NJ06280 (government) · No conflicts declared
- Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women (Peer-reviewed) · Funded by Ultimate Wellness Systems, Inc. (industry) · Authors declare a conflict of interest
Who’s saying this
- Nature’s Craft — a brand: sells its own vitamins and supplements
How we know who this is
- “At Nature’s Craft, we pride ourselves on our wide range of supplements made with only the best ingredients to address various health concerns.” (their page)
Raspberry ketone supplements can be deadly.
Supports — suggestivehealth and safety evidence
Studied in: adult taking OTC raspberry ketone weight-loss supplement (single case report).
Measured as an outcome.
- Resistant Polymorphic Ventricular Tachycardia in a Patient Taking Raspberry Ketones Weight Loss Supplement (Peer-reviewed) · Funding not checked · No conflicts declared
Who’s saying this
- Yahoo — a publisher: advertising solutions for advertisers and partners
How we know who this is
- “For 30 years and counting, Yahoo has become second nature for millions of people around the world.” (their page)
- “Our solutions ensure advertisers and partners reach the right audiences and achieve positive results.” (their page)
Raspberry ketone burns fat and helps you lose weight.
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women (Peer-reviewed) · Funded by Ultimate Wellness Systems, Inc. (industry) · Authors declare a conflict of interest
Who’s saying this
- ABC News — a publisher
How we know who this is
- “ABC News is not responsible for the content of external Internet sites.” (their page)