Roll Call

“Raspberry Ketones?”Here!raspberry ketone

Varies by source

Hasn’t appeared in a scanned product yet.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

A synthetic or naturally derived aromatic compound structurally similar to capsaicin and synephrine, found in trace amounts in red raspberries and produced commercially for supplement use.

Why it’s used

Taken by some for weight management, based on claims of fat metabolism effects popularized in weight-loss marketing.

What the evidence says

Evidence for raspberry ketones' effects on fat metabolism comes almost entirely from animal or in-vitro studies at doses far exceeding what would be found in food or typical supplement servings. Controlled human clinical trials on raspberry ketones alone are lacking, so claims about weight loss in humans are not supported by direct evidence.

Where we looked

There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.

  • PubMed: 3 records · searched September 2026"Raspberry Ketones"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract])
  • PubMed: 1 record · searched September 2026"Raspberry Ketones"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH]
  • PubMed: 13 records · searched September 2026"Raspberry Ketones"[Title/Abstract]

This says what this database holds under these terms. It is not a finding that no research exists.

Context

Most cited research uses rodent models, and results have not been replicated in human trials.

Insufficient dataToo little has been studied to say either way.

Rumors

  1. Raspberry ketone is a miracle fat burner that helps you lose weight.

    Not gradedhealth and safety evidence

    Sources cited — no verdict reached.

    What was measured is not yet noted.

    Who’s saying this

  2. Raspberry ketone suppresses appetite.

    Does not support — suggestivehealth and safety evidence

    Studied in: male and female C57BL/6J mice fed high-fat or low-fat diet and orally dosed with raspberry ketone (200 or 400 mg/kg) for 14 days.

    Measured as an outcome.

    Who’s saying this

    • Walmart — a retailer: sells fashion, home goods and more; Walmart+ membership
      How we know who this is
      • “The trademarks Walmart and the Walmart Spark design are registered with the US Patent and Trademark Office.” (their page)
      • “Annual members can save $380 per year!” (their page)
  3. Raspberry ketone may be toxic to the heart and affect the reproductive system.

    Does not support — suggestivehealth and safety evidence

    Studied in: male and female mice fed high-fat or low-fat diet, given oral raspberry ketone for 14 days.

    Measured as a biomarker.

    Who’s saying this

    • Live Science — a publisher: science news; part of Future US Inc, a digital media group
      How we know who this is
      • “Live Science is part of Future US Inc, an international media group and leading digital publisher.” (their page)