“Red Wine?”Here!
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A dried extract or powder made from red wine or red grape skins, used as a source of polyphenols such as resveratrol, anthocyanins, and other flavonoids.
Why it’s used
Taken by some for general antioxidant support, echoing the reputation of red wine polyphenols in cardiovascular research.
What the evidence says
Much of the public interest in red wine traces to epidemiological associations between moderate wine consumption and cardiovascular outcomes, and to laboratory research on resveratrol, one of its many compounds. Isolated resveratrol has its own clinical literature with mixed human results at studied doses. "Red wine extract" as a standalone supplement ingredient — as opposed to whole wine consumption or isolated resveratrol — has not been established in oral-supplement trials.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 893 records · searched September 2026
"Red Wine"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 34 records · searched September 2026
"Red Wine"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 5135 records · searched September 2026
"Red Wine"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Evidence appears to exist for whole-wine epidemiology and for isolated resveratrol, but not for dried red wine extract itself as a supplement ingredient. A reviewer would look for trials using standardized resveratrol content or whole-wine consumption studies, not this generic extract.
Rumors
Red wine extract gives you all the health benefits of red wine without the alcohol.
Does not support — suggestivehealth and safety evidence
Studied in: adults with high-normal blood pressure or grade 1 hypertension.
Measured as a biomarker.
- Red wine polyphenols do not lower peripheral or central blood pressure in high normal blood pressure and hypertension (Peer-reviewed) · Funding not checked
- Consumption of a Polyphenol-Rich Grape-Wine Extract Lowers Ambulatory Blood Pressure in Mildly Hypertensive Subjects (Peer-reviewed) · Funding not checked · Authors declare a conflict of interest
- Fine wine or sour grapes? A systematic review and meta-analysis of the impact of red wine polyphenols on vascular health (Peer-reviewed) · Funded by BBSRC MIBTP Studentship; Arthritis Research UK (government) · Authors declare a conflict of interest
Who’s saying this
- Swanson Vitamins — a brand: sells its own vitamins and supplements
How we know who this is
- “At Swanson Vitamins, integrity means you get exactly what's promised: Safe, pure, effective supplements that you can trust.” (their page)
Red wine extract supplements can cause digestive upset or headache.
Does not support — suggestivehealth and safety evidence
Studied in: mildly hypertensive adults taking grape‑wine extract capsules (800 mg polyphenols/day) for 4 weeks.
Measured as an outcome.
- Consumption of a Polyphenol-Rich Grape-Wine Extract Lowers Ambulatory Blood Pressure in Mildly Hypertensive Subjects (Peer-reviewed) · Funding not checked · Authors declare a conflict of interest
- Resveratrol (Database) · Funding not checked
Who’s saying this
- greenskybio.com — we couldn’t open the site to see who runs it
Red wine extract provides a broad antioxidant shield that neutralizes free radicals.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- greenskybio.com — we couldn’t open the site to see who runs it
Red wine extract supplements support cardiovascular health by protecting the cardiovascular system from free radicals.
Unresolvedhealth and safety evidence
Studied in: adults with high-normal blood pressure or mild/grade 1 hypertension.
Measured as an outcome.
- Fine wine or sour grapes? A systematic review and meta-analysis of the impact of red wine polyphenols on vascular health (Peer-reviewed) · Funded by BBSRC MIBTP Studentship; Arthritis Research UK (government) · Authors declare a conflict of interest
- Red wine polyphenols do not lower peripheral or central blood pressure in high normal blood pressure and hypertension (Peer-reviewed) · Funding not checked
- Consumption of a Polyphenol-Rich Grape-Wine Extract Lowers Ambulatory Blood Pressure in Mildly Hypertensive Subjects (Peer-reviewed) · Funding not checked · Authors declare a conflict of interest
Who’s saying this
- Swanson Vitamins — a brand: sells its own vitamins and supplements
How we know who this is
- “At Swanson Vitamins, integrity means you get exactly what's promised: Safe, pure, effective supplements that you can trust.” (their page)