Roll Call

Red Yeast Rice

Biotech

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Rice fermented with the mold Monascus purpureus, which produces compounds called monacolins, including monacolin K, which is chemically identical to the active ingredient in the prescription drug lovastatin.

Why it’s used

Taken to help manage cholesterol levels as an alternative to conventional statin therapy.

What the evidence is for

lowering LDL cholesterol.

What the evidence says

Systematic reviews and clinical trials report that red yeast rice can lower LDL cholesterol, an effect attributed to its monacolin K content. However, monacolin K levels vary widely and are inconsistently regulated between products, so the actual dose delivered is often unknown, and this variability is a recognized limitation of the evidence.

Dose studied

5–10 mg — monacolin K content used in cholesterol trials.

Context

Clinical trials have generally used red yeast rice extracts providing roughly 5 to 10 milligrams of monacolin K per day, taken for periods of 8 to 12 weeks or longer.

Evidence: suggestiveSome credible evidence exists, but the question is not settled.

Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.