“Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)?”Here!Vitamin B2
Appears in 4 scanned products.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
Riboflavin is a water-soluble B vitamin the body uses to convert food into usable energy. Riboflavin 5'-phosphate is its active, phosphorylated form, sometimes used because it does not require an extra conversion step in the body.
Why it’s used
Taken to meet daily riboflavin needs and, separately, sometimes taken by people looking into migraine prevention.
What the evidence is for
reducing migraine frequency at high supplemental doses.
What the evidence says
NIH ODS confirms riboflavin is essential for energy metabolism and that deficiency is rare in people eating a varied diet but can occur with poor intake or certain conditions. Separately, several clinical trials have looked at high-dose riboflavin (well above the RDA) for reducing migraine frequency, with some showing modest benefit, though study quality and size vary and it is not considered a settled first-line finding.
Dose studied
1.1–1.3 mg — adult RDA, per NIH ODS.
Context
The adult RDA is 1.1-1.3 mg/day. Migraine trials have generally used doses far above the RDA, commonly cited around 400 mg/day, over periods of three months or more, in adult populations with frequent migraine.
Rumors
Reducing migraine frequency at high supplemental doses.
Supports — suggestivehealth and safety evidence
Studied in: adults with migraine.
Measured as an outcome.
- Riboflavin - Health Professional Fact Sheet (Regulatory) · Funding not checked
How much is a reference amount
- 1.1 mg a dayfor adults 19 and over, women · Recommended Dietary Allowance
No upper limit has been set — the data was not sufficient to set one, which is a gap in the research rather than a finding about safety.
- 1.3 mg a dayfor adults 19 and over, men · Recommended Dietary Allowance
No upper limit has been set — the data was not sufficient to set one, which is a gap in the research rather than a finding about safety.
The legacy corpus stored this as a range, 1.1–1.3 mg. It is not a range: it is the RDA for women and the RDA for men. No UL was set.
Every applicable line is shown because we don’t know which one is yours, and a reference intake is a target for a population, not a threshold for harm.