Roll Call

Saccharomyces boulardii — answers to S. boulardii, a probiotic yeast

Biotech

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A strain of yeast, related to baker's yeast, sold as a probiotic in capsule or powder form.

Why it’s used

Taken to support gut flora, particularly around antibiotic use or travel, and to help manage occasional diarrhea.

What the evidence is for

reducing risk of antibiotic-associated diarrhea.

What the evidence says

Systematic reviews and meta-analyses, including a Cochrane review, report that S. boulardii can reduce the risk of antibiotic-associated diarrhea and may help with acute infectious diarrhea in children, though study quality varies and effect sizes are modest. Evidence for broader digestive or immune claims is much weaker.

Context

Trials typically dose this yeast by colony-forming units rather than by weight, so protocols are not directly comparable to mass-based dosing. Most studied populations were people already taking antibiotics or with acute diarrhea, not the general population.

Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.