Serratiopeptidase — answers to serrapeptase
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A protein-digesting enzyme originally isolated from bacteria found in the gut of silkworms. It is produced commercially through fermentation for use in supplements.
Why it’s used
Taken by some for support with inflammation or swelling, including after minor surgery or dental procedures.
What the evidence says
Clinical trials of serratiopeptidase exist but are generally small, older, and of inconsistent quality, making it difficult to draw firm conclusions from the published literature as a whole.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 1 record · searched August 2026
"Serratiopeptidase"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 141 records · searched August 2026
"Serratiopeptidase"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Studied protocols have varied widely in dose, duration, and the condition examined, which limits comparison across trials.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.