Roll Call

Silymarin — answers to Milk thistle extract

Plant

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A group of plant compounds (flavonolignans) extracted from milk thistle seeds, of which silybin is the main component.

Why it’s used

Taken by some to support liver health.

What the evidence says

According to the NIH National Center for Complementary and Integrative Health, clinical trials of silymarin for liver conditions have produced mixed results, and there is not enough reliable evidence to say it improves liver disease outcomes in people.

Context

Clinical trials have used a wide range of doses and preparations, often standardized to silybin content, with no single dose established as most studied or most effective.

Evidence: weakThe claim is made, but the evidence behind it is poor.

Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.