“Spleen?”Here!spleen glandular
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A dried, powdered extract made from the spleen of cattle or other animals, sold as a "glandular" supplement.
Why it’s used
Taken by some to support immune function, following the same glandular-therapy tradition as other organ extracts.
What the evidence says
There is no NIH ODS fact sheet and no well-designed human trials demonstrating an effect of oral spleen extract on immune function. As with other glandulars, digestion breaks dietary protein into amino acids before absorption, which is not accounted for in the underlying premise.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 19244 records · searched September 2026
"Spleen"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 76 records · searched September 2026
"Spleen"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 165412 records · searched September 2026
"Spleen"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
No standardized dosing protocols exist in clinical research.
Rumors
Desiccated spleen supplements help the body rebuild healthy spleen tissue.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- Snow Holistic Health — a professional body or practice: functional medicine and chiropractic clinic; sells Standard Process supplements
How we know who this is
- “At Snow Holistic Health, we find the root cause of your symptoms and build you a real plan: functional medicine , nutrition, and chiropractic care in Lake Charles.” (their page)
- “Snow Holistic Health is authorized to sell Standard Process Products, but is not a partner, franchisor, joint venturer, agent, or employee of Standard Process Inc.” (their page)
- Snow Holistic Health — a professional body or practice: functional medicine and chiropractic clinic; sells Standard Process supplements
Beef spleen is the richest natural source of heme iron and supports blood/iron levels.
Supports — suggestivehealth and safety evidence
Measured as a biomarker.
- Total Iron and Heme Iron Content and their Distribution in Beef Meat and Viscera (Peer-reviewed) · Funded by Fondo Nacional de Desarrollo Científico y Tecnologico (Fondecyt) (government) · No conflicts declared
Who’s saying this
- Ancestral Supplements — a brand: sells freeze-dried grass fed beef organ supplements
How we know who this is
- “Understanding that not everyone can access high-quality beef organs, Ancestral Supplements sought out the most pristine grass fed cattle found only in New Zealand and Australia.” (their page)
- “Today, Ancestral Supplements is known as the founder and leader of “The Beef Organ Supplement Movement.”” (their page)
Spleen supplements boost the immune system.
Supports — suggestivehealth and safety evidence
Studied in: patients with advanced breast cancer undergoing chemotherapy.
Measured as a biomarker.
- Safety and efficacy of spleen aminopeptide oral lyophilized powder for improving quality of life and immune response in patients with advanced breast cancer: a multicenter, randomized, double-blind, placebo-controlled clinical trial (Peer-reviewed) · Funded by Beijing Key Specialty (government) · No conflicts declared
Who’s saying this
- Kiltz Health — a brand: sells health coaching sessions promoting carnivore/keto diet
How we know who this is
- “Dr. Robert J. Kiltz is a double board-certified OB/GYN and Reproductive Endocrinologist, the founder of CNY Fertility, and the visionary behind Kiltz Health and the Kiltz Mighty Tribe (KMT).” (their page)
- “Book a private, 30-minute one-on-one session with a Kiltz Health Certified Coach to receive a personalized roadmap for your health goals.” (their page)
Glandular supplements made from cattle organs can expose users to mad cow disease (vCJD).
Sources cited — check not cleared.
A claim about bovine glandular supplements as a group, not this substance alone.
Measured as a biomarker.
- Use of Materials Derived From Cattle in Human Food and Cosmetics (Regulatory) · Funding not checked
- Import Alert 17-04 (Regulatory) · Funding not checked
Who’s saying this
- Center for Food Safety — an advocacy group: campaigns against industrial agriculture, toxic pesticides and GMOs
How we know who this is
- “Center for Food Safety empowers people, supports farmers, and protects the Earth from the impacts of industrial agriculture.” (their page)
- “For more than 25 years, Center for Food Safety’s pioneering legal, policy, and campaign strategies have led a revolution to transform our food system—curbing the use of toxic pesticides and GMOs in agriculture and promoting an organic, ecological, and just food and farming system.” (their page)
Beef spleen supplements support digestive health (and allergy health).
Not gradedhealth and safety evidence
Sources cited — no verdict reached.
What was measured is not yet noted.
- Efficacy and safety of spleen aminopeptide oral solution for children with allergic rhinitis and adenoid hypertrophy: a randomised trial (Peer-reviewed) · Funded by National Natural Science Foundation Youth Fund; Development Center for Medical Science and Technology National Health Commission of People’s Republic of China (government) · No conflicts declared
Who’s saying this
- Walmart — a retailer: sells fashion, home goods and more; Walmart+ membership
How we know who this is
- “The trademarks Walmart and the Walmart Spark design are registered with the US Patent and Trademark Office.” (their page)
- “Annual members can save $380 per year!” (their page)