Spleen — answers to spleen glandular
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A dried, powdered extract made from the spleen of cattle or other animals, sold as a "glandular" supplement.
Why it’s used
Taken by some to support immune function, following the same glandular-therapy tradition as other organ extracts.
What the evidence says
There is no NIH ODS fact sheet and no well-designed human trials demonstrating an effect of oral spleen extract on immune function. As with other glandulars, digestion breaks dietary protein into amino acids before absorption, which is not accounted for in the underlying premise.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 76 records · searched August 2026
"Spleen"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 164888 records · searched August 2026
"Spleen"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
No standardized dosing protocols exist in clinical research.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.