Sucrase
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A digestive enzyme, produced naturally in the small intestine and also derived from yeast or fungal sources for supplement use, that breaks down the sugar sucrose into glucose and fructose.
Why it’s used
Included in digestive enzyme blends taken to support the breakdown of dietary sugar, particularly by people who report sensitivity to sucrose-containing foods.
What the evidence says
There is no NIH ODS fact sheet on sucrase as a supplement ingredient. A purified enzyme replacement exists as a prescription product for a rare inherited condition called congenital sucrase-isomaltase deficiency, used under medical supervision; this is distinct from general over-the-counter digestive-enzyme supplementation, for which human evidence is minimal.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 4 records · searched August 2026
"Sucrase"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 3733 records · searched August 2026
"Sucrase"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Clinical study of enzyme replacement has focused on diagnosed sucrase-isomaltase deficiency rather than general digestive support, and there is no established dosing protocol for supplement blends sold to the general public.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.