Sulforaphane — answers to broccoli sprout compound
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A sulfur-containing compound formed when a precursor called glucoraphanin, present in broccoli and other cruciferous vegetables, is converted by the enzyme myrosinase. It is most concentrated in young broccoli sprouts.
Why it’s used
Taken by some to support the body's natural detoxification enzyme activity, and marketed as a source of antioxidant-related compounds.
What the evidence says
Small human studies suggest sulforaphane or broccoli sprout extracts can increase activity of certain detoxification-related enzymes and have been explored in a handful of small trials on airway inflammation and other outcomes, but the overall human evidence base remains preliminary, with no NIH ODS fact sheet or major consensus review yet establishing a clear effect.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 33 records · searched August 2026
"Sulforaphane"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 3536 records · searched August 2026
"Sulforaphane"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Trials have used broccoli sprout extracts of varying, often unstandardized potency over periods of weeks to months, making direct comparison between studies difficult.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.