“Sulforaphane?”Here!broccoli sprout compound
Hasn’t appeared in a scanned product yet.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A sulfur-containing compound formed when a precursor called glucoraphanin, present in broccoli and other cruciferous vegetables, is converted by the enzyme myrosinase. It is most concentrated in young broccoli sprouts.
Why it’s used
Taken by some to support the body's natural detoxification enzyme activity, and marketed as a source of antioxidant-related compounds.
What the evidence says
Small human studies suggest sulforaphane or broccoli sprout extracts can increase activity of certain detoxification-related enzymes and have been explored in a handful of small trials on airway inflammation and other outcomes, but the overall human evidence base remains preliminary, with no NIH ODS fact sheet or major consensus review yet establishing a clear effect.
Where we looked
There was no paper to cite here, so this is the search instead — run it yourself and see what we saw.
- PubMed: 868 records · searched September 2026
"Sulforaphane"[Title/Abstract] AND (review[pt] OR "safety assessment"[Title/Abstract] OR "risk assessment"[Title/Abstract] OR toxicology[Title/Abstract] OR toxicity[Title/Abstract] OR characterization[Title/Abstract] OR characterisation[Title/Abstract]) - PubMed: 34 records · searched September 2026
"Sulforaphane"[Title/Abstract] AND ("dietary supplements"[MeSH] OR supplementation[Title/Abstract] OR supplement[Title/Abstract] OR supplements[Title/Abstract] OR "oral administration"[Title/Abstract]) AND (randomized controlled trial[pt] OR clinical trial[pt] OR meta-analysis[pt] OR systematic review[pt]) AND humans[MeSH] - PubMed: 3562 records · searched September 2026
"Sulforaphane"[Title/Abstract]
This says what this database holds under these terms. It is not a finding that no research exists.
Context
Trials have used broccoli sprout extracts of varying, often unstandardized potency over periods of weeks to months, making direct comparison between studies difficult.
Rumors
Sulforaphane interferes with thyroid function by blocking iodine uptake.
We haven’t found evidence strong enough to support this or rule it out.
What was measured is not yet noted.
Who’s saying this
- longevity.technology — we couldn’t open the site to see who runs it
Sulforaphane supplements detoxify the body by activating its own antioxidant and detoxifying enzymes.
Sources cited — check not cleared.
Studied in: adults with COPD.
Measured as a biomarker.
- Lack of Effect of Oral Sulforaphane Administration on Nrf2 Expression in COPD: A Randomized, Double-Blind, Placebo Controlled Trial (Peer-reviewed) · Funding not checked
Who’s saying this
- metagenics.com — we couldn’t open the site to see who runs it
Sulforaphane prevents cancer by inhibiting cancer cell growth.
Supports — suggestivehealth and safety evidence
Studied in: former smokers at high risk for lung cancer.
Measured as a biomarker.
- Efficacy and tolerability of sulforaphane in the therapeutic management of cancers: a systematic review of randomized controlled trials (Peer-reviewed) · Funded by Qatar University · No conflicts declared
- Randomized phase II clinical trial of sulforaphane in former smokers at high risk for lung cancer (Peer-reviewed) · Funding not checked
- Effect of Sulforaphane in Men with Biochemical Recurrence after Radical Prostatectomy (Peer-reviewed) · Funding not checked
Who’s saying this
- Broc Shot — a brand: sells broccoli seed sulforaphane supplements
How we know who this is
- “Broc Shot is available in capsule and powder form, with each serving delivering the same guaranteed dose of active sulforaphane — no less than 12 mg per serving.” (their page)
Sulforaphane supplements help people with autism.
Supports — suggestivehealth and safety evidence
Studied in: children and adults diagnosed with autism spectrum disorder.
Measured as an outcome.
- The effect of sulforaphane on autism spectrum disorder: systematic review and meta-analysis (Peer-reviewed) · Funding not checked
- Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder (Peer-reviewed) · Funding not checked
Who’s saying this
- Girlboss — a publisher: media company for women's careers
How we know who this is
- “Today, Girlboss is a modern media company providing women all over the world with the tools and mindset to succeed.” (their page)