Vitamin B12 (cyanocobalamin) — answers to Vitamin B12
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A synthetic, stable form of vitamin B12, an essential nutrient the body needs for nerve function and red blood cell formation. Cyanocobalamin is converted to the body's active B12 forms after absorption.
Why it’s used
Taken to meet daily B12 needs or correct a diagnosed deficiency, which can occur with age, certain digestive conditions, or a vegan diet lacking animal-source foods.
What the evidence is for
correcting vitamin B12 deficiency.
What the evidence says
The NIH Office of Dietary Supplements confirms vitamin B12 supplementation, including cyanocobalamin, effectively raises B12 levels and reverses deficiency-related symptoms such as fatigue and nerve problems. Evidence for benefits beyond correcting a deficiency, such as boosting energy in people who are not deficient, is not established.
Dose studied
2.4–1000 mcg — adult RDA up through doses used to treat diagnosed deficiency, per NIH ODS.
Context
The adult RDA and studied deficiency-treatment doses are both expressed in micrograms; clinical treatment of diagnosed deficiency has used doses well above the RDA under medical supervision, though the RDA itself covers ordinary dietary sufficiency.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.