“Vitamin B2 (riboflavin 5-phosphate)?”Here!riboflavin
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As a supplement
Talk to your doctor or pharmacist.
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The active, phosphorylated form of riboflavin, an essential B vitamin involved in energy metabolism.
Why it’s used
Taken to meet riboflavin needs and correct deficiency, and by some for migraine support based on separate research using plain riboflavin.
What the evidence is for
preventing and correcting riboflavin deficiency.
What the evidence says
NIH's Office of Dietary Supplements confirms riboflavin's established role in preventing and correcting deficiency, which can cause skin and eye symptoms. Separate, smaller clinical trials have examined high-dose riboflavin for migraine frequency, with some positive findings, though this research is less extensive than the deficiency evidence.
Dose studied
1.1–1.3 mg — adult RDA for riboflavin, per NIH ODS.
Context
Migraine studies have generally used doses around 400 mg per day of riboflavin over several months, distinct from the much smaller amounts needed to prevent ordinary dietary deficiency.
Rumors
Correcting riboflavin deficiency, which causes cracked lips and sores at the corners of the mouth, sore throat, itchy red eyes, hair loss and skin disorders.
Supports — establishedhealth and safety evidence
Measured as a biomarker.
- Riboflavin - Health Professional Fact Sheet (Regulatory) · Funding not checked
How much is a reference amount
- 1.1 mg a dayfor adults 19 and over, women · Recommended Dietary Allowance
No upper limit has been set — the data was not sufficient to set one, which is a gap in the research rather than a finding about safety.
- 1.3 mg a dayfor adults 19 and over, men · Recommended Dietary Allowance
No upper limit has been set — the data was not sufficient to set one, which is a gap in the research rather than a finding about safety.
The legacy corpus stored this as a range, 1.1–1.3 mg. It is not a range: it is the RDA for women and the RDA for men. No UL was set.
Every applicable line is shown because we don’t know which one is yours, and a reference intake is a target for a population, not a threshold for harm.