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Vitamin B6 (Pyridoxine HCl) — answers to Vitamin B6, pyridoxine

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A water-soluble B vitamin, here in its hydrochloride salt form, involved in amino acid, glucose, and lipid metabolism and in the production of neurotransmitters.

Why it’s used

Taken to meet daily vitamin B6 needs and to support nervous system and red blood cell function, particularly when dietary intake is low.

What the evidence is for

correcting vitamin B6 deficiency and supporting normal metabolic and neurological function.

What the evidence says

NIH ODS confirms vitamin B6 is essential and that deficiency causes recognized problems including anemia and neurological symptoms; oral supplementation reliably corrects deficiency and low status. Evidence for benefits beyond correcting deficiency (e.g., mood, PMS symptoms) is weaker and mixed.

Dose studied

1.3–100 mg — adult RDA up to the tolerable upper intake level, per NIH ODS.

Context

NIH ODS lists an adult RDA around 1.3–1.7 mg/day depending on age and sex, and a tolerable upper intake level of 100 mg/day for adults; long-term high-dose intake has been linked to sensory nerve problems in some cases.

Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.