Roll Call

“Vitamin B6 (Pyridoxine HCl)?”Here!Vitamin B6, pyridoxine

Synthetic

Appears in 1 scanned product.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

A water-soluble B vitamin, here in its hydrochloride salt form, involved in amino acid, glucose, and lipid metabolism and in the production of neurotransmitters.

Why it’s used

Taken to meet daily vitamin B6 needs and to support nervous system and red blood cell function, particularly when dietary intake is low.

What the evidence is for

correcting vitamin B6 deficiency and supporting normal metabolic and neurological function.

What the evidence says

NIH ODS confirms vitamin B6 is essential and that deficiency causes recognized problems including anemia and neurological symptoms; oral supplementation reliably corrects deficiency and low status. Evidence for benefits beyond correcting deficiency (e.g., mood, PMS symptoms) is weaker and mixed.

Dose studied

1.3–100 mg — adult RDA up to the tolerable upper intake level, per NIH ODS.

Context

NIH ODS lists an adult RDA around 1.3–1.7 mg/day depending on age and sex, and a tolerable upper intake level of 100 mg/day for adults; long-term high-dose intake has been linked to sensory nerve problems in some cases.

Rumors

  1. Correcting vitamin B6 deficiency, which causes microcytic anemia, cracked lips and a swollen tongue, dermatitis, depression and confusion, and seizures in infants.

    Supports — establishedhealth and safety evidence

    Measured as an outcome.

How much is a reference amount

  • 1.3 mg a dayfor adults 19–50 · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

  • 1.5 mg a dayfor adults 51–70, women · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

  • 1.7 mg a dayfor adults 51–70, men · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

  • 1.5 mg a dayfor adults 71 and over, women · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

  • 1.7 mg a dayfor adults 71 and over, men · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

The worksheet planned one adults_19_plus row for B6. The DRI is age-differentiated: it rises at 51, and it differentiates by sex only from 51 onwards. Five rows, not one.

Every applicable line is shown because we don’t know which one is yours, and a reference intake is a target for a population, not a threshold for harm.