Roll Call

“Vitamin B6 (pyridoxine hydrochloride)?”Here!vitamin B6

Synthetic

Hasn’t appeared in a scanned product yet.

As a supplement

Talk to your doctor or pharmacist.

Roll Call does not check drug interactions or assess personal safety.

A synthetic, water-soluble form of vitamin B6, a nutrient the body needs for amino acid and neurotransmitter metabolism.

Why it’s used

Taken to meet daily vitamin B6 needs or to correct a documented deficiency.

What the evidence is for

correcting vitamin B6 deficiency and supporting normal metabolism.

What the evidence says

NIH ODS confirms vitamin B6 is required for normal metabolism and nerve function, and that deficiency causes recognized symptoms correctable by supplementation. Evidence for benefits beyond correcting deficiency, such as mood or cognitive claims, is weaker and not well established.

Dose studied

1.3–100 mg — adult RDA up to the tolerable upper intake level, per NIH ODS.

Context

NIH ODS lists the adult RDA at roughly 1.3 to 1.7 mg per day depending on age and sex, with a tolerable upper intake level of 100 mg per day for adults, based on nerve-related effects seen at high intakes in research.

Rumors

  1. Correcting vitamin B6 deficiency, which causes microcytic anemia, cracked lips and a swollen tongue, dermatitis, depression and confusion, and seizures in infants.

    Supports — establishedhealth and safety evidence

    Measured as a biomarker.

How much is a reference amount

  • 1.3 mg a dayfor adults 19–50 · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

  • 1.5 mg a dayfor adults 51–70, women · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

  • 1.7 mg a dayfor adults 51–70, men · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

  • 1.5 mg a dayfor adults 71 and over, women · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

  • 1.7 mg a dayfor adults 71 and over, men · Recommended Dietary Allowance

    Upper limit 100 mg a day, from food and supplements together.

The worksheet planned one adults_19_plus row for B6. The DRI is age-differentiated: it rises at 51, and it differentiates by sex only from 51 onwards. Five rows, not one.

Every applicable line is shown because we don’t know which one is yours, and a reference intake is a target for a population, not a threshold for harm.