Roll Call

Vitamin B6 — answers to pyridoxine

Synthetic

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Vitamin B6 is a water-soluble vitamin that exists in several chemical forms (pyridoxine, pyridoxal, pyridoxamine and their phosphates). It is required for amino acid, glucose, and lipid metabolism and for red blood cell and nervous system function.

Why it’s used

Taken to correct or prevent deficiency and to support normal metabolism and nervous system function.

What the evidence is for

correcting vitamin B6 deficiency and supporting normal metabolism.

What the evidence says

According to NIH's Office of Dietary Supplements, vitamin B6 has an established role in metabolism and deficiency is well characterized, with correction of deficiency reliably improving related symptoms. Evidence for benefits beyond correcting insufficiency — such as mood or cognitive claims sometimes made for B6 supplements — is far weaker and not well supported.

Dose studied

1.3–100 mg — adult RDA up to the tolerable upper intake level, per NIH ODS.

Context

The adult Recommended Dietary Allowance is roughly 1.3 to 1.7 mg per day depending on age and sex; the tolerable upper intake level for adults is set at 100 mg per day due to nerve-related effects seen with prolonged high intake.

Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.