Vitamin E
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A fat-soluble vitamin that exists as several related compounds (tocopherols and tocotrienols), most commonly alpha-tocopherol in supplements.
Why it’s used
Taken to meet a dietary requirement and, as an antioxidant, sometimes for general cellular support.
What the evidence is for
correcting vitamin E deficiency.
What the evidence says
NIH ODS confirms vitamin E is essential and corrects deficiency, which is rare and usually tied to fat-malabsorption conditions. Large trials testing vitamin E supplementation for heart disease or cancer prevention in people without deficiency have largely found no benefit, and some found possible harm at high doses, so evidence for benefits beyond correcting deficiency is weak.
Dose studied
15–1000 mg — RDA to tolerable upper intake level, adults, per NIH ODS.
Context
NIH ODS lists an RDA of 15 mg/day for adults and a tolerable upper intake level of 1,000 mg/day from supplemental forms; most efficacy trials used doses well above the RDA and found inconsistent results.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.