Vitamin K2 (as MK7 Menaquinone) — answers to vitamin K2, menaquinone-7
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A form of vitamin K, a fat-soluble vitamin. Menaquinone-7 (MK-7) is one of several menaquinone forms, distinguished from the plant-based phylloquinone (vitamin K1) form and known for a longer half-life in the body.
Why it’s used
Taken to support bone and cardiovascular health, based on vitamin K's role in activating proteins involved in calcium handling in bone and blood vessels.
What the evidence is for
supporting markers of bone and vascular calcium handling.
What the evidence says
NIH ODS notes vitamin K is essential for blood clotting and bone metabolism, with an Adequate Intake rather than an RDA due to limited data. Evidence specific to MK-7 for bone density and vascular calcification comes from a number of smaller trials and is considered suggestive rather than settled; larger, longer trials are limited, and effects on hard outcomes like fracture risk are not firmly established.
Dose studied
45–180 mcg — typical daily doses used in MK-7 bone and vascular trials.
Context
Trials of MK-7 for bone and vascular markers have commonly used daily doses in the range of roughly 45 to 180 micrograms, generally over many months, with most studies conducted in postmenopausal populations rather than the general public.
Educational information, not medical or safety advice. Consult a professional for allergies or medical concerns.