“Vitamin K2 (as MK7 Menaquinone)?”Here!vitamin K2, menaquinone-7
Appears in 2 scanned products.
As a supplement
Talk to your doctor or pharmacist.
Roll Call does not check drug interactions or assess personal safety.
A form of vitamin K, a fat-soluble vitamin. Menaquinone-7 (MK-7) is one of several menaquinone forms, distinguished from the plant-based phylloquinone (vitamin K1) form and known for a longer half-life in the body.
Why it’s used
Taken to support bone and cardiovascular health, based on vitamin K's role in activating proteins involved in calcium handling in bone and blood vessels.
What the evidence is for
supporting markers of bone and vascular calcium handling.
What the evidence says
NIH ODS notes vitamin K is essential for blood clotting and bone metabolism, with an Adequate Intake rather than an RDA due to limited data. Evidence specific to MK-7 for bone density and vascular calcification comes from a number of smaller trials and is considered suggestive rather than settled; larger, longer trials are limited, and effects on hard outcomes like fracture risk are not firmly established.
Dose studied
45–180 mcg — typical daily doses used in MK-7 bone and vascular trials.
Context
Trials of MK-7 for bone and vascular markers have commonly used daily doses in the range of roughly 45 to 180 micrograms, generally over many months, with most studies conducted in postmenopausal populations rather than the general public.
Rumors
Vitamin K2 as MK-7 moves calcium out of the arteries and into the bones.
Does not supporthealth and safety evidence
Studied in: patients with symptomatic coronary artery disease/cardiovascular or kidney disease.
Measured as an outcome.
- Two Years of Menaquinone-7 Supplementation and Coronary Artery Calcification: A Randomized Clinical Trial (Peer-reviewed) · Funding not checked
- Vitamin K supplementation and vascular calcification: a systematic review and meta-analysis of randomized controlled trials (Peer-reviewed) · Funding not checked · No conflicts declared
Who’s saying this
- Center for Better Bones — a professional body or practice: bone health consultations and programs; also sells supplements
How we know who this is
- “She is the founder of the Center for Better Bones and the Better Bones Foundation, and author of Better Bones, Better Body — the first comprehensive guide to natural bone health.” (their page)
- “The Center offers individualized nutrition and lifestyle consultations, bone health programs, and guided support for those dealing with osteoporosis, osteopenia, and fracture recovery.” (their page)
How much is a reference amount
- 90 mcg a dayfor adults 19 and over, women · Adequate Intake
No upper limit has been set — the data was not sufficient to set one, which is a gap in the research rather than a finding about safety.
- 120 mcg a dayfor adults 19 and over, men · Adequate Intake
No upper limit has been set — the data was not sufficient to set one, which is a gap in the research rather than a finding about safety.
An AI, set on phylloquinone (K1) intakes. It is applied to the menaquinone rows because it is the vitamin K AI and panels declare them as vitamin K; the FNB did not set separate values per form. No UL.
Every applicable line is shown because we don’t know which one is yours, and a reference intake is a target for a population, not a threshold for harm.